The study will consist of people living in the Manchester region who are diagnosed with
chronic IBS and who want to volunteer for the study. Informed consent forms will be
signed by all volunteers and these forms will be kept in the file. The number of people
who will participate in the study was determined using G Power analysis and the number of
samples was calculated as 1st group 30 people, 2nd group 30 people and 3rd group 30
people, totalling 90 people. Individuals with IBS were randomly divided into three groups
and diet only [low FODMAP diet (fermentable oligo-di-mono-saccharides and polyols)], diet
The low FODMAP (fermentable oligo-di-mono-saccharides and polyols) diet to be applied for
the nutrition of the participants will be given to each individual as training before the
study. In our study, vagus nerve stimulation will be applied through the ear. Aerobic
exercises will be demonstrated one-to-one and the application of the patients will be
monitored and the vagustim device will be applied to the groups in the clinic. In the
intervention group, the vagustim device consisting of earphones placed in the outer ear,
which can be selected as S, M, L according to the size of the individual's ear, and a
tens device connected to the earphones will be used. The earphones will be placed to hit
the tragus and concha and the device will be applied for 30 minutes with a pulse duration
of less than 500 microseconds, frequency of 10 Hz and modulated TENS mode, and the
current intensity will be adjusted according to the sensory threshold of the individual.
The group given aerobic exercise will be given walking exercise for 4 weeks, 3 days a
week, for at least 30 minutes and at a moderate intensity not exceeding 50-70% of the
maximal heart rate (if the pulse cannot be counted during sports, the criterion is that
the person can talk comfortably). In our study, the decision of aerobic exercise to be
given to a group was made by reviewing the literature.
Heart rate variability of the participants before and after the study will be evaluated
with Polar H10 HR heart rate sensor. The bowel sounds of the participants before and
after the study will be measured using a Littmann 4100 model electronic stethoscope. The
first and last measurements will be measured according to the same standards and these
standards are as follows: The measurements will be performed 2 hours after the last meal
of the person who has not smoked for the last 2 hours before the measurements and has not
consumed alcohol (permitted amount) in the last 12 hours. At the same time,
'Sociodemographic Form', 'SF-36', 'International Physical Activity Questionnaire Short
Last 7 Days Self-Administered Form', 'Bristol Stool Form Scale (BSFS)' and 'Irritable
Bowel Syndrome- Symptom Severity Scale (IBS-SSS)' scales will be applied to the
individuals.
