EMDR Treatment of Conditioned Nausea and Vomiting in Cancer Survivors

Last updated: September 25, 2025
Sponsor: University Medical Center Groningen
Overall Status: Active - Recruiting

Phase

N/A

Condition

Vomiting

Colic

Lactose Intolerance

Treatment

EMDR therapy

Clinical Study ID

NCT06769165
19946
  • Ages > 16
  • All Genders

Study Summary

To explore the effectiveness of EMDR therapy treatment in reducing symptoms of chemotherapy-induced conditioned nausea and vomiting in (former) patients with cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Previously pathologically confirmed diagnosis of cancer

  • Previously treated with systemic cancer therapy

  • Persistent complaints (more than 2 months) of conditioned nausea and/or vomiting

  • Able to understand spoken and written Dutch

  • 18 years or older

Exclusion

Exclusion Criteria:

  • Ongoing psychiatric treatment

  • EMDR therapy contraindications (dissociative disorders, personality disorders orsevere somatic disorders (e.g. cardiac arrhythmias))

  • Complex type 2 trauma

  • Known with recent conditions / non-anti-cancer medication which can elicit nausea (e.g. pregnancy or alcohol abuses)

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: EMDR therapy
Phase:
Study Start date:
November 01, 2025
Estimated Completion Date:
August 01, 2026

Study Description

Conditioned nausea and vomiting is a common side effect of anti-cancer treatment, and while strategies like antiemetics exist, their effectiveness is limited. Conditioned nausea and vomiting can possibly be addressed through Eye Movement Desensitization and Reprocessing (EMDR) therapy. EMDR therapy is a therapeutic intervention, proven to be effective in the treatment of post-traumatic stress disorder (PTSD), and promising in treating a range of other conditions. At the UMCG, EMDR therapy is used on a small scale to treat conditioned nausea with positive results, although more rigorous research is needed to fully establish its efficacy. This study aims to explore the effectiveness of EMDR therapy treatment in reducing symptoms of chemotherapy-induced conditioned nausea and vomiting in (former) patients with cancer.

Connect with a study center

  • University Medical Center Groningen

    Groningen 2755251, Provincie Groningen 2755249 9713 GZ
    Netherlands

    Active - Recruiting

  • University Medical Center Groningen

    Groningen, 9713 GZ
    Netherlands

    Site Not Available

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