Prophylactic Mesh Reinforcement After Open Aortic Aneurysm Repair

Last updated: June 2, 2025
Sponsor: Hôpital Fribourgeois
Overall Status: Active - Recruiting

Phase

N/A

Condition

Aneurysm

Cardiovascular Disease

Heart Disease

Treatment

Prophylactic retromuscular mesh reinforcement

Clinical Study ID

NCT06762561
2348
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The goal of this retrospective observational study is to evaluate whether prophylactic mesh reinforcement during abdominal wall closure can prevent incisional hernias (IH) in patients undergoing open abdominal aortic aneurysm (AAA) repair. The main questions it aims to answer are:

  • Does mesh reinforcement reduce the incidence of incisional hernias?

  • What is the frequency of associated postoperative complications? Researchers will compare the outcomes of patients who underwent mesh-reinforced closures to literature-reported outcomes for non-mesh cases to assess differences in IH incidence and complications.

Participants will:

  • Undergo clinical follow-ups and abdominal ultrasounds to detect IH.

  • Complete quality-of-life questionnaires (EQ-5D and PROMIS).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult patients (≥18 years old) who underwent open abdominal aortic aneurysm (AAA)repair with prophylactic retromuscular mesh reinforcement between January 2019 andJanuary 2024

  • Availability of complete medical records, including preoperative history, surgicaldetails, and postoperative follow-up data

  • Attendance at a clinical follow-up examination at least one year after the procedure

  • General informed consent signed for the use of medical data for research purposes

Exclusion

Exclusion Criteria:

  • Patients with incomplete or missing medical records, including preoperative,intraoperative, or follow-up data

  • Patients who required a re-laparotomy involving incision or suture of theprophylactic mesh and subsequently developed an incisional hernia.

  • Patients who did not attend the required clinical follow-up examination at least oneyear postoperatively.

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: Prophylactic retromuscular mesh reinforcement
Phase:
Study Start date:
June 01, 2025
Estimated Completion Date:
October 31, 2026

Connect with a study center

  • HFR Hopitaux Fribourgeois

    Villars-sur-Glane,
    Switzerland

    Active - Recruiting

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