Phase
Condition
Obesity
Metabolic Disorders
Diabetes Prevention
Treatment
Laparoscopic Roux-en Y Gastric bypass (RYGB)- Conventional approach
Laparoscopic Roux-en Y Gastric bypass (RYGB)- Tailored approach
Clinical Study ID
Ages 18-65 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Age: 18-65 years
Body Mass Index (BMI): BMI ≥ 40 kg/m² or BMI ≥ 35 kg/m² with at least one obesity-related comorbidity (e.g., type 2 diabetes, hypertension, obstructive sleep apnea).
ASA - less than or equal to 3
Informed Consent: Ability and willingness to provide written informed consent andcomply with procedures.
Previous Weight Loss Attempts: Documentation of previous attempts at weight lossthrough diet, exercise, or medical management.
Exclusion
Exclusion Criteria:
Previous Bariatric Surgery: Prior bariatric or major gastrointestinal surgery thatmight affect the outcome of RYGB.
Severe Cardiopulmonary Conditions: Significant cardiac or pulmonary conditions thatpose a high surgical risk (e.g., severe congestive heart failure, severe chronicobstructive pulmonary disease).
Uncontrolled Psychiatric Disorders: Severe psychiatric illness or substance abuseissues that are not well-controlled, including eating disorders.
Pregnancy: Current pregnancy or plans to become pregnant within 12 monthspost-surgery.
Malignancy: Active malignancy or history of malignancy requiring treatment in thepast 5 years (excluding non-melanoma skin cancer).
Severe Liver Disease: Cirrhosis or significant liver dysfunction (e.g., Child-Pugh Bor C).
Inability to Comply: Patients who are unable or unwilling to comply with thepostoperative follow-up schedule and dietary requirements.
Chronic Use of Medications: Chronic use of medications known to affect weight ormetabolism significantly, such as corticosteroids or antipsychotics.
Other Medical Conditions: Any other medical condition or surgical finding that, inthe opinion of the investigators, would make the patient unsuitable for the study.
Study Design
Connect with a study center
GEM Hospital and Research Center
Coimbatore, Tamil nadu 641045
IndiaActive - Recruiting

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