The Comparative Efficacy of Standard Treatment Plus Ribavirin vs Standard Treatment Alone in Preventing Clinically Significant Hemorrhage in Patients With Dengue Fever

Inclusion Criteria:

• Male and female patients aged 18 years and above.

• Hospitalized patients diagnosed with dengue fever, confirmed via:

• Positive Dengue NS1 antigen test

• Dengue IgM antibodies

• Dengue RNA PCR.

• Patients presenting with various severities of illness, as classified by the WHOdengue severity classification.

Exclusion Criteria:

• Patients taking antiplatelet or anticoagulant medications.

• Patients with known bleeding disorders (e.g., hemophilia, von Willebrand disease,end-stage renal disease, or liver cirrhosis).

• Patients with HIV undergoing antiviral therapy.

• Pregnant women.

• Patients with hypersensitivity to Ribavirin.

• Patients with WHO Grade 1 bleeding (few petechiae without clinical significance).