Comparison Of Efficacy Of Iron Polymaltose Complex And Ferrous Sulphate In Iron Deficiency Anemia In Pediatric Patients

Last updated: December 17, 2024
Sponsor: Arooj Khan
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anemia

Treatment

Ferrous sulfate

Iron Polymaltose Complex

Clinical Study ID

NCT06742528
591/DME/KMC
  • Ages 6-5
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study aims to compare the efficacy of two iron preparation for the management of children presented with iron deficiency anemia. Ferrous sulphate and lron polymaltose (ferric form) are most commonly used preparations. Both drugs are easily available in market and are often recommended by pediatriclans. The efficacy, bioavail.tbilily, side effects and cost of these preparations vary. This study is designed to find out a drug with better efficacy that can be used for treatment of iron deficiency anemia in local population.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients having iron deficiency anemia

Exclusion

Exclusion Criteria:

  1. Patients diagnosed as congenital aplastic anemia or thalassemia (Determined frommedical record).

  2. Patients who were transfused in previous 4 weeks (will be determined on history)

  3. Children having mal-absorption syndrome and diarrheal illnesses. (will be determinedon history and medical record)

  4. Gastrointestinal bleeding suggested by history of hematemesis (bloody vomit), melena (black colored stools) or bloody stools.

Study Design

Total Participants: 198
Treatment Group(s): 2
Primary Treatment: Ferrous sulfate
Phase:
Study Start date:
January 10, 2024
Estimated Completion Date:
January 10, 2025

Study Description

Anemia remains a condition with high prevalence in populations worldwide. It is predominantly associated with nutritional status and socioeconomic conditions or hereditary diseases. The majority of anemia cases are linked to iron deficiency-named iron-deficiency anemia resulting from low intake of iron-rich foods in the diet, or from substantial blood loss.

This study aims to compare the efficacy of two iron preparation for the management of children presented with iron deficiency anemia. Ferrous sulphate and lron polymaltose (ferric form) are most commonly used preparations. Both drugs are easily available in market and are often recommended by pediatriclans. The efficacy, bioavail.tbilily, side effects and cost of these preparations vary. This study is designed to find out a drug with better efficacy that can be used for treatment of iron deficiency anemia in local population.

Connect with a study center

  • Khyber Teaching Hospital

    Peshawar, KPK 25000
    Pakistan

    Active - Recruiting

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