Hormonal Management of Heavy Menstrual Bleeding in Adolescents

Last updated: December 18, 2024
Sponsor: University Hospital, Geneva
Overall Status: Active - Recruiting

Phase

N/A

Condition

Female Hormonal Deficiencies/abnormalities

Hemorrhage

Thrombocytopenic

Treatment

N/A

Clinical Study ID

NCT06740929
2024-01578
  • Ages < 25
  • Female

Study Summary

The goal of this study is to evaluate whether hormonal medications (such as contraceptive pill, patch, injectable progestins and hormonal intra-uterine device) have similar efficacy at managing heavy menstrual bleeding in adolescents with a bleeding disorder compared to those without. We also aim to assess the quality of life and hemoglobin and iron levels in this population.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adolescents and young adults aged < 26yo

  • Presenting to the gynecology consultation at HUG

  • Diagnosed with heavy menstrual bleeding (PBAC > 100)

  • Willing to initiate a hormonal medication to manage heavy menstrual bleeding

Exclusion

Exclusion Criteria:

  • Pregnancy or planning to become pregnant during the study period

  • Already using hormonal medication for menstrual management and/or contraception

  • Known anatomical uterine pathology

  • Using anticoagulant or antiaggregant agents

Study Design

Total Participants: 163
Study Start date:
December 01, 2024
Estimated Completion Date:
December 31, 2027

Study Description

Adolescents with heavy menstrual bleeding and willing to start a hormonal medication to reduce menstrual flow are included. At baseline and during the study period, questionnaires and blood tests are performed. Adolescents with a bleeding disorder are compared to those without. Follow-up is 1 year.

Connect with a study center

  • Geneva University Hospitals

    Geneva, 1205
    Switzerland

    Active - Recruiting

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