Improved Prescribing for Older Nursing Home Patients

Last updated: December 9, 2024
Sponsor: Amsterdam UMC, location VUmc
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Systematic multidisciplinary medication review + ACP (SMMR+)

Clinical Study ID

NCT06731361
839160003
  • Ages > 65
  • All Genders

Study Summary

Research aim:

To investigate the effect of training health care professionals in medication assessments on the medication use of nursing home residents with a limited life expectancy (< 1.5-2 years).

The core of the training is to tailor medication use to (palliative) treatment goals of nursing home residents.

Design:

A cluster randomized controlled trial on long term care wards in nursing homes, with the nursing home care organisations as unit of randomisation. The investigators intent to include 6 organisations and 450 nursing home patients. The research starts in september and lasts 1 year and 3 months. Eligible patients are nursing home patients of 65 years and older with a limited life expectancy (< 1.5-2 year) of long term care wards.

Intervention:

The intervention includes a method in which healthcare professionals (medical practitioner, pharmacist and care worker) are trained to tailor medication to the (palliative) treatment goals of nursing home patients with a limited life expectancy. The training consists of 2 components: 1) medication assessment, and 2) advance care planning (ACP). In the intervention group, healthcare professionals receive the training in combination with supporting tools and educational materials, in the control group care continues as normal. The allocation ratio for control and intervention groups is 1:1. A process evaluation will take place simultaneously with the intervention study. Data collection takes place before the start of the intervention (T0), after 6 months (T1) and after 12 months (T2).

Outcome measures:

The primary outcome measure is potential under- and over-treatment with medication. The secondary outcome measure is experienced involvement in decision-making (measured with a short questionnaire based on the revised PATD (patients' attitude towards deprescribing)). Tertiary outcome measures are: quality of life, deaths, falls, hospital admissions/acute first aid referrals and pain.

Discussion:

The intervention is expected to result in a decrease in chronic and preventive medication prescriptions, an increase in medication for symptom treatment and more involvement (and satisfaction) of the nursing home resident in decision-making, without adverse effects.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Nursing home patients:

  • Age 65years and above

  • Living at long term care wards in nursing homes

  • Living at a long term care ward for at least 4 weeks before start of the study

Exclusion

Exclusion Criteria:

  • Temporary nursing home patients (i.e. geriatric rehabilitation orend-of-life/hospice care)

  • Life expectancy < 4 weeks

  • Life expectancy clearly > 1.5 - 2 years (i.e. patients with Huntingtons disease)

Study Design

Total Participants: 450
Treatment Group(s): 1
Primary Treatment: Systematic multidisciplinary medication review + ACP (SMMR+)
Phase:
Study Start date:
September 10, 2024
Estimated Completion Date:
December 01, 2025

Study Description

Additional information on the method:

We included 2 nursinghome organizations in september, 2 in october, and 3 in november.

Connect with a study center

  • Zorggroep Apeldoorn, location Randerode, De Hofstede and De Windkanter

    Apeldoorn, Gelderland 7334DV
    Netherlands

    Site Not Available

  • Zorggroep Noordwest-Veluwe, locaties Weideheem en de Arcade

    Harderwijk, Gelderland 3844 JW
    Netherlands

    Site Not Available

  • Cordaan, location Nieuw Vredenburgh

    Amsterdam, Noord Holland 1057 DZ
    Netherlands

    Active - Recruiting

  • Amaris, Location Alporti and Rubina

    Hilversum, Noord-Holland 1215 SE
    Netherlands

    Site Not Available

  • AxionContinu, location Isselwaerde and de Schutse

    Ijsselstein, Utrecht 3401 BN
    Netherlands

    Active - Recruiting

  • Zorgspectrum, location de Plataan

    Vianen, Utrecht 4133 GX
    Netherlands

    Active - Recruiting

  • Dignis, location de Veldspaat

    Groningen, 9743XV
    Netherlands

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.