Mobile Intervention for Mental Health of Family Caregivers in Thailand

Last updated: June 3, 2026
Sponsor: Brigham and Women's Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Depression

Panic Disorders

Anxiety Disorders

Treatment

Usual Care Group

Caregiver Mental Health Mobile Application (CAMMA) Intervention

Caregiver Mental Health Mobile Application Intervention

Clinical Study ID

NCT06722287
2023P001212
5R21MH131043-02
4R33MH131043-03
  • Ages 18-80
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The primary objective of this study is to evaluate the effectiveness of the CAMMA intervention in reducing psychological distress among family caregivers of adults with chronic conditions in Thailand. Psychological distress is operationalized as depressive symptoms, anxiety symptoms, and perceived stress.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Adult (age 18 +) family caregiver (CG)

  2. Has a minimum of 4 months of experience as a caregiver and provides at least 4 hoursa day of care to the care recipient (CR);

  3. Access to a mobile device with internet access

Exclusion

Exclusion Criteria:

  • Caregiver who refuses to provide informed consent

Study Design

Total Participants: 400
Treatment Group(s): 3
Primary Treatment: Usual Care Group
Phase:
Study Start date:
September 01, 2023
Estimated Completion Date:
June 30, 2028

Study Description

The R33 randomized controlled trial will test whether CAMMA leads to meaningful reductions in depressive symptoms, anxiety, and perceived stress among family caregivers, compared with an active control condition. Consistent with the underlying caregiving risk framework, the trial will also examine hypothesized mediators-including self-care skills, caregiving self-efficacy, caregiver burden, and engagement with intervention components-to clarify mechanisms of action.

By embedding the intervention within existing service delivery structures and engaging frontline care managers and community care givers as active participants, the R33 trial is designed to generate evidence that is both clinically meaningful and implementation-relevant. This approach responds directly to the need for scalable, sustainable strategies to support caregiver mental health in low- and middle-income country settings and provides a strong empirical foundation for future dissemination and scale-up.

Connect with a study center

  • Ministry of Public Health

    Bangkok,
    Thailand

    Active - Recruiting

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