Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children.

Last updated: April 7, 2025
Sponsor: University Hospital, Toulouse
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

VExUS evaluation ultrasound

Clinical Study ID

NCT06695546
RC31/24/0457
  • Ages 1-18
  • All Genders

Study Summary

Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact. This score was initially evaluated and validated on an adult population. ) In children, there is only one study looking at the use and applicability of this VExUS score, highlighting its feasibility in a paediatric population, as well as a possible correlation between elevated central venous pressure and altered renal Doppler (one of the score's components).

Eligibility Criteria

Inclusion

Inclusion Criteria:

Children aged between 1 and 18 years, receiving extrarenal purification with UF > 10 ml/kg, bleeding > 10 ml/kg or vascular filling > 10 ml/kg

Exclusion

Exclusion Criteria:

  • Refusal of the patient or opposition of one or both holders of parental authority.

  • Minors with parental authority.

  • Ultrafiltration time > 6h.

  • Curarized patient, known abnormality of the hepatorenal venous network.

  • Patient agitated or poor tolerance of the examination.

  • Parents under court protection, guardianship or curatorship.

Study Design

Total Participants: 56
Treatment Group(s): 1
Primary Treatment: VExUS evaluation ultrasound
Phase:
Study Start date:
December 10, 2024
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • CHU Toulouse

    Toulouse, 31000
    France

    Active - Recruiting

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