Preventing Mental Disorders Among Women Internally Displaced by War in Ukraine: The SHAWL Trial

Last updated: March 27, 2025
Sponsor: Boston Medical Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Depression

Schizophrenia And Schizoaffective Disorders (Pediatric)

Kleptomania

Treatment

Attention control

Acceptance and Commitment Therapy

Clinical Study ID

NCT06679114
H-45281
R34MH134077
  • Ages > 18
  • Female

Study Summary

This study is a randomized controlled trial among 120 recently displaced women to determine the effectiveness of a single-session Acceptance and Commitment Therapy (ACT) group therapy on prevention of development of mental health disorders or worsened mental health symptoms.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18 or over

  • Identify as a displaced woman within one year of migration

  • Endorsing mild to moderate depressive symptoms (subscale score between 3 and 7)and/or anxiety symptoms (subscale score between 2 and 6) on the Mental HealthAssessment Inventory (MHAI) but not exceeding the maximum score for either subscale (i.e., not exceeding 7 on the depressive symptoms subscale and not exceeding 6 onthe anxiety symptoms subscale)

  • Ability to provide informed consent

  • Speak Ukrainian or Russian

Exclusion

Exclusion Criteria:

  • Diagnosis of a depressive or anxiety disorder, or symptoms necessitating urgentreferral for evaluation of suicidal or homicidal ideation

  • Receipt of psychiatric care for depression or anxiety in the past 5 years

  • A severe medical problem that inhibits ability to participate in the trial

Study Design

Total Participants: 120
Treatment Group(s): 2
Primary Treatment: Attention control
Phase:
Study Start date:
March 27, 2025
Estimated Completion Date:
March 31, 2026

Study Description

The war in Ukraine has provoked the world's current largest humanitarian displacement: since February 2022, one-third of Ukrainians have been forced to leave their homes, resulting in upwards of 7 million internally displaced persons. Estimates suggest that 60% of Ukraine's displaced persons are women, who face stressors including difficulty accessing necessary primary health and psychological care, restricted access to food and stable housing, and increased strain from separation from their social networks and additional family care responsibilities.

Early reports from Ukraine consistently describe the psychological distress that displaced women are presently experiencing. It is anticipated that nearly one in five people exposed to conflict will develop mental disorders, notably depressive and anxiety disorders. Thus, improving access to mental health prevention programs that mitigate development of mental disorders for women in Ukraine is critical.

This study will adapt a community-based Acceptance and Commitment Therapy (ACT) intervention to prevent the development symptoms of depression and anxiety among women displaced by war in Ukraine. ACT is an evidence-based approach that uses acceptance, mindfulness and behavioral change processes to improve psychological flexibility. Recently displaced women who screen positive for symptoms of depression and anxiety will be recruited. The investigators plan to adapt and evaluate a single-session ACT group intervention to limit effects of mental health distress among these displaced women.

The central hypothesis of this research is that an ACT-based intervention delivered in a humanitarian context will help displaced women in Ukraine learn skills to improve psychological flexibility, thereby decreasing symptoms of depression and anxiety and ultimately mitigating onset of mental disorders.

Connect with a study center

  • Alliance for Public Health

    Kyiv,
    Ukraine

    Active - Recruiting

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