Phase
Condition
Heartburn
Treatment
N/AClinical Study ID
Ages > 60 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion criteria for AD cohort:
adult ≥60 years old
diagnosis of AD by a neurologist (confirmed with imaging, spinal tap, behavioral testing)
no prior history of other neurological diseases (aside from stroke which has resolved with no current symptoms)
no prior history of respiratory diseases
no prior history of head and neck surgery/head and neck cancer/radiation to head and neck region
consuming some form of oral intake
able to follow basic directions
able/willing to provide consent/assent.
Exclusion Criteria for AD Cohort:
individual <60 years old
Diagnosis of another type of dementia
History of neurological/respiratory diseases
History of head and neck surgery/head and neck cancer/radiation to head and neck region
not consuming any oral intake
Unable to follow basic directions
Unable to provide consent based on the University of California, San Diego Brief Assessment of Capacity to Consent (UBACC), score <15 OR provide assent and a legal guardian provides consent.
Inclusion criteria for care partners of individuals with AD will be:
care partner of an individual with AD
willing to complete questionnaires/participate in an interview.
Exclusion Criteria for Caregivers of Individuals with AD:
not the primary caregiver of an individual with AD
unwilling to complete questionnaires/semi-structured interview
Inclusion criteria for community-dwelling adults will be:
adult ≥60 years old
no prior history of neurological diseases (aside from stroke which has resolved with no current symptoms)
no prior history of respiratory diseases
- no prior history of head and neck surgery/head and neck cancer/radiation to head and neck region 4) no prior history of swallowing difficulties based on participant report. 5) Score ≥25th percentile based on sex/age/education/race on the Montreal Cognitive Assessment (MOCA)
Exclusion Criteria for Healthy Cohort:
individual <60 years old
history of neurological disease
history of respiratory disease
history of head and neck surgery/head and neck cancer/radiation to head and neck region
history of swallowing difficulties
Score <25th percentile based on sex/age/education/race on the Montreal Cognitive Assessment (MOCA)
Study Design
Study Description
Connect with a study center
Vanderbilt University Medical Center
Nashville, Tennessee 37232
United StatesActive - Recruiting
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