An Observational Study of Coronary Microvascular Disease of China

Last updated: August 19, 2025
Sponsor: Henan Institute of Cardiovascular Epidemiology
Overall Status: Active - Recruiting

Phase

N/A

Condition

Angina

Treatment

N/A

Clinical Study ID

NCT06676137
HenanICE202410
  • Ages 18-85
  • All Genders

Study Summary

Non-obstructive coronary heart disease refers to patients with angina pectoris without significant narrowing of the epicardial vessels. Coronary microvascular disease(CMD) is a kind of non-obstructive coronary heart disease, and its clinical detection rate is increasing, seriously affecting the quality of life of patients, and increasing the risk of cardiovascular adverse events, but its mechanism has not been fully understood. This study will prospectively collect patients who meet the diagnosis of CMD, observe the development and outcome of the disease, and explore its occurrence and development mechanism.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Angina symptoms

  2. Objective evidence of myocardial ischemia

  3. Coronary angiography was normal,irregular tube wall, or stenosis <50%

Exclusion

Exclusion Criteria:

  1. People under the age of 18

  2. Non-cardiogenic chest pain and other heart conditions such as variant angina,cardiomyopathy, myocarditis or valvular heart disease

Study Design

Total Participants: 500
Study Start date:
November 11, 2024
Estimated Completion Date:
October 10, 2029

Connect with a study center

  • Fuwai central China cardiovascular hospotial

    Zhengzhou, 450003
    China

    Active - Recruiting

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