A Study to Learn How Different Forms of the Study Medicine Called PF-07976016 Are Taken Up Into the Blood in Healthy Adults

Last updated: September 16, 2025
Sponsor: Pfizer
Overall Status: Completed

Phase

1

Condition

Healthy Volunteers

Treatment

PF-07976016 Formulation B

PF-07976016 Formulation A

Clinical Study ID

NCT06670170
C5541005
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The primary purpose of this study is to measure and compare the amount of study drug in your blood after a single dose of two formulations of study drug.

Eligibility Criteria

Inclusion

Key Inclusion Criteria:

  • Overtly healthy as determined by medical evaluation including medical history,physical examination, laboratory tests, vital signs and ECG assessments.

  • Willing to provide consent and follow study requirements

  • Total body weight >110lbs (50kg)

Exclusion

Key Exclusion Criteria:

  • Any condition affecting drug absorption, clinically significant laboratory values

  • HIV, HepB & HepC

  • Serious illness or hospitalization, or other condition, that may increase the riskof study participation or, in the investigator's judgment, make the participantinappropriate for the study.

  • Use of prescription or non-prescription drugs within a specified timeframe prior tothe first dose of study intervention

  • positive urine drug test at screening/admission

  • History of alcohol abuse or repeated binge drinking and/or any other illicit druguse or dependence within 6 months of screening

  • Use of tobacco/nicotine containing products more than the equivalent of 5cigarettes/day or 2 chews of tobacco/day

Study Design

Total Participants: 12
Treatment Group(s): 2
Primary Treatment: PF-07976016 Formulation B
Phase: 1
Study Start date:
November 05, 2024
Estimated Completion Date:
January 17, 2025

Connect with a study center

  • Pfizer Clinical Research Unit - New Haven

    New Haven, Connecticut 06511
    United States

    Site Not Available

  • Pfizer Clinical Research Unit - New Haven

    New Haven 4839366, Connecticut 4831725 06511
    United States

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.