A Study to Learn How Different Forms of the Study Medicine Called PF-07976016 Are Taken Up Into the Blood in Healthy Adults

Last updated: March 10, 2025
Sponsor: Pfizer
Overall Status: Completed

Phase

1

Condition

Healthy Volunteers

Treatment

PF-07976016 Formulation B

PF-07976016 Formulation A

Clinical Study ID

NCT06670170
C5541005
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The primary purpose of this study is to measure and compare the amount of study drug in your blood after a single dose of two formulations of study drug.

Eligibility Criteria

Inclusion

Key Inclusion Criteria:

  • Overtly healthy as determined by medical evaluation including medical history,physical examination, laboratory tests, vital signs and ECG assessments.

  • Willing to provide consent and follow study requirements

  • Total body weight >110lbs (50kg)

Exclusion

Key Exclusion Criteria:

  • Any condition affecting drug absorption, clinically significant laboratory values

  • HIV, HepB & HepC

  • Serious illness or hospitalization, or other condition, that may increase the riskof study participation or, in the investigator's judgment, make the participantinappropriate for the study.

  • Use of prescription or non-prescription drugs within a specified timeframe prior tothe first dose of study intervention

  • positive urine drug test at screening/admission

  • History of alcohol abuse or repeated binge drinking and/or any other illicit druguse or dependence within 6 months of screening

  • Use of tobacco/nicotine containing products more than the equivalent of 5cigarettes/day or 2 chews of tobacco/day

Study Design

Total Participants: 12
Treatment Group(s): 2
Primary Treatment: PF-07976016 Formulation B
Phase: 1
Study Start date:
November 05, 2024
Estimated Completion Date:
January 17, 2025

Connect with a study center

  • Pfizer Clinical Research Unit - New Haven

    New Haven, Connecticut 06511
    United States

    Site Not Available

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