Effect of Acupuncture on Postoperative Nausea and Vomiting

Last updated: March 14, 2025
Sponsor: Ankara City Hospital Bilkent
Overall Status: Completed

Phase

N/A

Condition

Colic

Vomiting

Lactose Intolerance

Treatment

No acupuncture

acupuncture

Clinical Study ID

NCT06669676
PONV
  • Ages > 18
  • All Genders

Study Summary

In this study, the hypothesis that bilateral acupuncture needling at the Neiguan (PC6) point during the intraoperative period, in addition to the 0.15 mg/kg dose of ondansetron (5-HT3 antagonist) frequently used for postoperative nausea and vomiting (PONV) prophylaxis in patients undergoing lumbar disc herniation surgery, would reduce the incidence of PONV was investigated. PONV was defined as the presence of nausea and vomiting within 24 hours postoperatively.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18 and above

  • ASA physical status I to II

  • One or two level lumbar disc herniation surgery under general anesthesia

Exclusion

Exclusion Criteria:

  • body mass index >35 kg/m²)

  • history of drug use

  • nausea and vomiting before surgery

  • psychiatric disorders

  • use of antipsychotic or antiemetic drugs

  • severe heart disease

  • central nervous system diseases

  • vertebrobasilar artery insufficiency

  • cytostatic therapy

  • vestibular diseases

  • renal and/or hepatic dysfunction

  • presence of fistula, neuropathy and paralysis in the extremity to be treated

  • patient's refusal to accept acupuncture

  • pregnant patients

  • presence of bleeding diathesis

  • patients in a condition where cooperation cannot be established in thepost-operative period (mental retardation etc.)

Study Design

Total Participants: 92
Treatment Group(s): 2
Primary Treatment: No acupuncture
Phase:
Study Start date:
November 07, 2024
Estimated Completion Date:
March 15, 2025

Study Description

The study will include patients aged 18 years and over, with (American Society of Anesthesiologists) ASA physical status I to II, and scheduled for one or two-level lumbar disc herniation surgery under general anesthesia. Patient characteristics (age, gender, body mass index, etc.) and postoperative nausea and vomiting (PONV) risk factors such as history of PONV, motion sickness, and history of not smoking will be recorded. The primary outcome parameter will be the incidence of PONV within 24 hours postoperatively. The severity of nausea in patients who develop nausea in the postoperative period will be assessed using a Likert scale between 0 and 10. PONV will be defined as vomiting, significant nausea (numerical rating scale [NRS] ≥4), and/or need for rescue medication. Patients will be assessed for PONV at 0, 2, 4, 12, and 24 hours using a Likert scale. Emetic attacks, pain and severity of pain, nausea and severity of nausea, need for additional analgesics, and administration of antiemetic rescue medication will be assessed as secondary outcome parameters. The severity of pain and nausea in patients who develop postoperative pain will be assessed using an 11-point numerical rating scale, where '0' indicates the absence of symptoms and '10' indicates the maximum severity. PONV within the first two hours will be defined as 'early', and within 2-24 hours after awakening will be defined as 'late'. Nausea will be defined as the desire to vomit, and vomiting will be defined as the forceful expulsion of stomach contents.

Connect with a study center

  • Ankara Bilkent City Hospital

    Ankara, Ankara, Çankaya 06800
    Turkey

    Site Not Available

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