The Impact of Vitamin D Supplementation in Hypertensive Vitamin D Deficient Patients.

Inclusion Criteria:

Hypertensive: Adult individual diagnosed with hypertension by a specialist (at least two systolic blood pressure readings above 140 mmHg or diastolic blood pressure readings above 90 mmHg, measured by a qualified professional following American Heart Association guidelines) managing hypertension through medication adherence, and regularly attending heart clinic appointments, with no other systemic diseases.

Control: Healthy adult individuals without hypertension or a history of other systemic diseases who volunteer and participate in the study, which will be recruited from relatives, friends, colleagues or patient accompanies. - (*Note: The healthy participants were included in the first part of the study before starting the clinical trial)

Exclusion Criteria:

1. Hypertensive individuals who have heart failure and other cardiac or systemicdiseases or with recent cardiovascular events.

2. Secondary hypertension 3. Hypertensive patients who require medication changeduring the course of the study.

3. Individuals on Lipid-lowering agents (e.g. simvastatin). 5. The use of othermedications affecting blood pressure is not part of the study protocol.

4. Any subjects on regular supplemental vitamin D or receiving multi-vitaminsregularly with vitamin D content of more than 880 IU, one month beforerecruitment.

5. Individuals with a BMI over 35 or less than 18 kg/m2. 8. Subjects with asignificant change in lifestyle, for example, exercise, weight change, or on aspecific dietary regimen during or in the previous four weeks of the study.

6. Subject diagnosed with neoplasm, or inflammatory or autoimmune diseases 10.Pregnant or lactating female