A Study to Assess Adults With CIDP Transitioning From IVIg to Efgartigimod PH20 SC

Last updated: April 3, 2026
Sponsor: argenx
Overall Status: Completed

Phase

4

Condition

Peripheral Neuropathy

Treatment

Efgartigimod PH20 SC

Clinical Study ID

NCT06637072
ARGX-113-2406
  • Ages > 18
  • All Genders

Study Summary

This study will measure how adults with CIDP receiving IVIg treatment adjust to efgartigimod PH20 SC. The study duration for each participant will be approximately 17 to 19 weeks.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Is at least 18 years of age and the local legal age of consent

  • Is diagnosed with CIDP (confirmed or possible CIDP) according to the criteria of theEuropean Academy of Neurology/Peripheral Nerve Society

  • Is being treated with IVIg every 3-6 weeks, on a stable dose and dosing interval (between 0.5-2 g/kg) for at least 3 doses

  • If receiving oral corticosteroids, this should be at a stable dose of less than 20mg a day or less than 40 mg every other day, for at least a month.

  • If receiving nonsteroidal immunosuppressive medication, this should be at a stabledose for at least 3 months

Exclusion

Exclusion Criteria:

  • Besides the indication under study, known autoimmune disease or any medicalcondition that would interfere with an accurate assessment of clinical symptoms ofCIDP or puts the participant at undue risk

  • Types of other polyneuropathy other than CIDP

Study Design

Total Participants: 23
Treatment Group(s): 1
Primary Treatment: Efgartigimod PH20 SC
Phase: 4
Study Start date:
December 10, 2024
Estimated Completion Date:
February 19, 2026

Connect with a study center

  • MedStar Washington Hospital Center

    Washington, District of Columbia 20010
    United States

    Site Not Available

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia 20010
    United States

    Site Not Available

  • MedStar Washington Hospital Center

    Washington D.C. 4140963, District of Columbia 4138106 20010
    United States

    Site Not Available

  • Neurology Associates PA

    Maitland, Florida 32751
    United States

    Site Not Available

  • Visionary Investigators Network

    Miami, Florida 33180
    United States

    Site Not Available

  • Neurology Associates PA

    Maitland 4163220, Florida 4155751 32751
    United States

    Site Not Available

  • Visionary Investigators Network

    Miami 4164138, Florida 4155751 33180
    United States

    Site Not Available

  • Northwestern Memorial Hospital

    Chicago, Illinois 60611
    United States

    Site Not Available

  • Northwestern Memorial Hospital

    Chicago 4887398, Illinois 4896861 60611
    United States

    Site Not Available

  • Velocity Clinical Research

    Lafayette, Louisiana 70508
    United States

    Site Not Available

  • Velocity Clinical Research

    Lafayette 4330145, Louisiana 4331987 70508
    United States

    Site Not Available

  • SRI International - ClinEdge

    Plymouth, Michigan 48170
    United States

    Site Not Available

  • SRI International - ClinEdge

    Plymouth 5006059, Michigan 5001836 48170
    United States

    Site Not Available

  • Velocity Clinical Research

    Raleigh, North Carolina 27607
    United States

    Site Not Available

  • Velocity Clinical Research

    Raleigh 4487042, North Carolina 4482348 27607
    United States

    Site Not Available

  • Erlanger Neuroscience Institute

    Chattanooga, Tennessee 37403
    United States

    Site Not Available

  • Vanderbilt University Medical Center

    Nashville, Tennessee 37232
    United States

    Site Not Available

  • Erlanger Neuroscience Institute

    Chattanooga 4612862, Tennessee 4662168 37403
    United States

    Site Not Available

  • Vanderbilt University Medical Center

    Nashville 4644585, Tennessee 4662168 37232
    United States

    Site Not Available

  • National Neuromuscular Research Institute

    Austin, Texas 78759
    United States

    Site Not Available

  • Horizon Clinical Research: Gill Neuroscience

    Cypress, Texas 21216
    United States

    Site Not Available

  • Northwest Houston Neurology - Cypress

    Cypress, Texas 77429
    United States

    Site Not Available

  • Cedar Health Research - Dallas

    Dallas, Texas 75251
    United States

    Site Not Available

  • National Neuromuscular Research Institute

    Austin 4671654, Texas 4736286 78759
    United States

    Site Not Available

  • Horizon Clinical Research: Gill Neuroscience

    Cypress 4684724, Texas 4736286 21216
    United States

    Site Not Available

  • Northwest Houston Neurology - Cypress

    Cypress 4684724, Texas 4736286 77429
    United States

    Site Not Available

  • Cedar Health Research - Dallas

    Dallas 4684888, Texas 4736286 75251
    United States

    Site Not Available

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