Meu-cinn for Gastric Mucosal Health in Adults With Functional Dyspepsia

Last updated: June 1, 2025
Sponsor: Pusan National University Yangsan Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Heartburn (Pediatric)

Heartburn

Bowel Dysfunction

Treatment

Meu-cinn

Placebo

Clinical Study ID

NCT06630455
12-2024-009
  • Ages 19-70
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This clinical trial aims to determine whether Meu-cinn promotes gastric mucosal health in adults with functional dyspepsia and to assess its safety.

The main questions are:

  • Does Meu-cinn promote gastric mucosal health in participants?

  • What side effects occur when participants take Meu-cinn?

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Rome IV-based functional dyspepsia-

Exclusion

Exclusion Criteria:

  • Patients with gastrointestinal symptoms requiring immediate drug treatment.

  • Individuals with a history of hypersecretory gastric disorders likeZollinger-Ellison syndrome.

  • Individuals who received Helicobacter pylori eradication therapy within 4 weeksprior to the trial.

  • Individuals who have taken nonsteroidal anti-inflammatory drugs, steroids,antibiotics, aspirin, antithrombotic agents, or acid suppressants within the lastmonth.

  • Individuals with a history of upper gastrointestinal surgery, stricture, bleeding,or procedures like esophageal dilation or mucosal resection within the last year.

  • Individuals with gastric ulcers (active or healing), duodenal ulcers (active orhealing), reflux esophagitis (LA grade A or higher), or malignant tumors identifiedwithin the last 6 months through endoscopy.

  • Patients with uncontrolled hypertension (resting BP ≥160/100 mmHg).

  • Patients with uncontrolled diabetes (fasting glucose ≥160 mg/dL).

  • Individuals with creatinine levels ≥ 2 times the upper limit of normal at theresearch institution.

  • Individuals with aspartate aminotransferase or alanine aminotransferase levels ≥ 2times the upper limit of normal at the research institution.

  • Alcohol abusers.

  • Individuals taking medications for psychiatric disorders (except those takingintermittent medication for sleep disorders).

  • Pregnant or breastfeeding women or those planning to become pregnant during theclinical trial period.

  • Individuals with allergies to any components of the study foods.

  • Individuals who participated in or plan to participate in another drug clinicaltrial within the last month.

  • Individuals deemed unsuitable for the study by the investigator for other reasons.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Meu-cinn
Phase:
Study Start date:
December 04, 2024
Estimated Completion Date:
December 31, 2025

Study Description

Researchers will compare Meu-cinn to placebo to evaluate their effectiveness in promoting gastric mucosal health.

Participants will:

  • Take Meu-cinn or a placebo daily for 8 weeks.

  • Visit the clinic at 1, 2, 4, and 8 weeks for checkups and tests.

Connect with a study center

  • Pusan National University Yangsan Hospital

    Yangsan, 50612
    Korea, Republic of

    Active - Recruiting

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