OsteoArticular Sepsis in Intensive Care unitS

Last updated: March 31, 2025
Sponsor: Assistance Publique - Hôpitaux de Paris
Overall Status: Active - Recruiting

Phase

N/A

Condition

Soft Tissue Infections

Osteomyelitis

Treatment

N/A

Clinical Study ID

NCT06627842
APHP241174
  • Ages > 18
  • All Genders

Study Summary

This is an ambispective observational study of patients admitted to critical care with a diagnosis of osteoarticular infection on material device (mainly knee and hip prostheses). The main objective of the study is to describe the profile, care trajectories during the stay (before or after surgery) and prognosis of patients admitted to critical care with such an infection. We also aim to compare prognosis between different groups of patients sharing the same profile and care trajectory, and to assess independent risk factors associated with 2-year mortality among the study population. Finally, we will describe the microbiological and resistance profile of severe osteoarticular device infections requiring critical care admission in France.

This is a descriptive and analytical observational study open to all French public and private hospitals.

Patient data will be retrieved prospectively from patient source files. Only 2-year data (vital status, functional data) will be collected specifically for the study, by telephone contact with the patient or his or her support person.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient at least 18 years old.

  • No opposition from the patient (or surrogate in case of death)

  • Stay in critical care (intensive care or continuing care) between 2018 and 2021 ofat least 48 hours, with the principal or associated diagnosis of an osteoarticular

Exclusion

Exclusion Criteria:

  • Patient under legal protection.

  • Pregnant or breast-feeding patient.

  • Patient deprived of liberty.

Study Design

Total Participants: 150
Study Start date:
January 29, 2025
Estimated Completion Date:
September 30, 2025

Connect with a study center

  • Hôpital Lariboisière

    Paris, 75010
    France

    Active - Recruiting

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