Effect of the "O-ring" Technique in Reducing Cerebrospinal Fluid Leak in Posterior Fossa Surgery: an Explorative Study

Last updated: April 29, 2025
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

O-ring technique

Clinical Study ID

NCT06620952
O'Ring
  • Ages > 18
  • All Genders

Study Summary

Posterior fossa surgery represents on of the most demanding procedure in neurosurgery. Retrosygmoid (RS), key-hole retrosygmoid (KR) and cerebellar hemispheric (CH) are the most common approaches used to access in this area. Despite they are not technically difficult to perform, these approaches can be burdened by postoperative cerebrospinal fluid (CSF) leakage, both at short and long-term follow-up, with an high risk of meningitis. Many techniques were employed to avoid this risk, but it can still be estimated between 2% and 11% according to literature1-4. Spena et al. reported a CSF leakage rate of 6.8% in a previous experience5. As a consequence, newer efforts are necessaries to avoid this potentially lethal complication. By this explorative study, we want to retrospectively analyzed our experience with a newer technique of bone closure, called O'Ring, in patients subdued to posterior fossa surgery by RS, KR and CH approaches, focusing on postoperative CSF leakage (primary objective), wound complications and subcutaneous CSF collections (secondary objectives).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • age ≥18 years,

  • availability of pre- and postoperative radiological and clinical data,

  • a follow-up period of at least 3 months.

Exclusion

Exclusion Criteria:

  • Lacking of clinical, radiological and surgical data

Study Design

Total Participants: 35
Treatment Group(s): 1
Primary Treatment: O-ring technique
Phase:
Study Start date:
July 16, 2024
Estimated Completion Date:
December 31, 2024

Connect with a study center

  • SC Neurochirurgia, Fondazione IRCCS Policlinico San Matteo

    Pavia, 27100
    Italy

    Site Not Available

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