Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy

Key Inclusion Criteria:

• Diagnosis of diabetes mellitus type 1 or type 2 with

• Glycosylated hemoglobin A1c (HbA1c) less than or equal to (≤) 9% and

• Presence of bilateral pain in lower extremities due to DPN (defined as asymmetric, length-dependent sensory or sensorimotor polyneuropathy) for atleast 1 year

Key Exclusion Criteria:

• Painful neuropathy other than DPN

• History of cardiac dysrhythmias requiring anti-arrhythmia treatment(s)

• History of a clinical atherosclerotic event, such as myocardial infarction orstroke, within the past 12 months

Other protocol defined Inclusion/Exclusion criteria may apply.