A Study of CM383 in Patients With Alzheimer's Disease Related Mild Cognitive Impairment and Mild Alzheimer's Disease

Inclusion Criteria:

• Voluntarily participate and have the subject and their legal guardian jointly signthe Informed Consent Form.

• The age of the subjects is between 50 and 85 years old.

• BMI≥19kg/m2 and ≤32.5 kg/m2, weight ≥45 kg and ≤100 kg at screening or baseline.

Exclusion Criteria:

• Cognitive impairment of subjects due to other medical or neurological factors (otherthan AD)

• History of stroke or transient ischemic attack, seizures, or other unexplained lossof consciousness within the past year

• With any mental illness that may interfere with the cognitive assessment of thesubjects.

• With history of moderate or severe renal dysfunction.

• With Uncontrolled stable hypertension.

• With history of severe trauma or major surgery in the 6 months prior to thescreening period, or planned surgery during the study.

• History of malignancy within 5 years prior to screening.