Phase
Condition
Stroke
Cardiac Ischemia
Cerebral Ischemia
Treatment
Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training
Clinical Study ID
Ages 18-80 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
18-80 years old with an ischemic or hemorrhagic stroke that occurred ≥6 monthsprior;
Ability to give consent;
Unilateral limb (left or right) weakness with Fugl Meyer-Upper Extremity Scale scoreof 19-53/60 points which indicates adequate arm/hand use for rehabilitation tasks;
active wrist flexion/extension ≥10° with active abduction/extension of thumb and atleast 1 digit ≥10° to further assure ability to participate in rehabilitation tasks;
Passive range of motion in affected shoulder, elbow and wrist within 20 degrees ofnormal values.
Exclusion
Exclusion Criteria:
Other concomitant neurological disorders affecting upper extremity motor function;
Presence of Dysphagia or aspiration difficulties;
Prior injury to vagus nerve;
Pregnancy;
Documented history of dementia before or after stroke;
Documented history of uncontrolled depression or psychiatric disorder either beforeor after stroke which could affect their ability to participate in the experiment;
Uncontrolled hypertension;
Botox injections within 4 weeks of the first day of rehabilitation therapy.
Study Design
Study Description
Connect with a study center
Medical University of South Carolina
Charleston, South Carolina 29403
United StatesActive - Recruiting
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