Phase
Condition
N/ATreatment
Folk Dance Multidomain Lifestyle Intervention
Self-Guided Multidomain Lifestyle Intervention
Clinical Study ID
Ages 65-75 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Age of 65-75 years
Proficiency in the local (Hungarian) language
Ability to perform all the three components of the Short Physical PerformanceBattery (score of at least 1 in each component)
Exclusion
Exclusion Criteria:
Previous diagnosis of mild cognitive impairment or dementia, including current useof medications for memory impairment
Suspected mild cognitive impairment or dementia after screening assessments, basedon clinical judgement
Contraindication for MRI scanning (e.g., metal implants, claustrophobia, excessivemovement, etc.)
History of any significant neurological condition, including Parkinson's disease,Huntington's disease, normal pressure hydrocephalus, brain tumours, progressivesupranuclear palsy, seizure disorder, subdural heamatoma, multiple sclerosis, orhistory of stroke, transient ischemic attack, or any significant head trauma withpersistent neurologic sequelae or known structural brain abnormalities
History of major depression, bipolar disorder, schizophrenia
Chronic medication use that could reasonably affect cognition, movement, or brainimaging measures
Active substance-related and addictive disorders
Current use of narcotics and psychoactive medications
Cognitive impairment based on the Mini-Mental State Examination (MMSE, raw scoreless than 26)
Reduced capacity for decision-making, unable to provide consent or complete studyassessments, based on clinical judgement
Conditions that prevent safe study participation
Current significant medical problems (e.g., malignant disease, cardiovasculardisease, conduction disorder)
History within the last 2 years of treatment for primary or recurrent malignantdisease
Poorly controlled or uncontrolled diabetes mellitus, cardiovascular, conduction, orpulmonary disease
Conditions that prevent cooperation: severe visual, auditory, or communicationimpairment (i.e., colour blindness, uncorrected hearing loss)
PI/Study Clinician discretion regarding medical status, suitability ofparticipation, or concerns about adherence to intervention
Ongoing participation in another clinical intervention study
Study Design
Study Description
Connect with a study center
Brain Imaging Centre, HUN-REN Centre for Natural Sciences
Budapest, 1117
HungarySite Not Available
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