Phase
Condition
N/ATreatment
ABBV-1088
Itraconazole (ITZ)
Placebo for ABBV-1088
Clinical Study ID
Ages > 18 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Body Mass Index (BMI) is > = 18.0 to < = 32.0 kg/m^2 after rounded to the tenthsdecimal, at Screening and upon confinement.
A condition of general good health, based upon the results of a medical history,physical examination, vital signs, laboratory profile and a 12-lead ECG.
Part 3 Only: Han Chinese Participant must be first-or second-generation Han Chineseof full Chinese parentage. First-generation participants will have been born inChina to two participants and four grandparents also born in China of full Chinesedescent. Second-generation participants born outside of China must have two parentsand four grandparents born in China of full Chinese descent. Participants mustmaintain a typical Chinese lifestyle, including consuming a typical Chinese diet. OR
Japanese Participant must be first-or second-generation Japanese of full Japaneseparentage. First-generation participants will have been born in Japan to two parentsand four grandparents also born in Japan of full Japanese descent. Second-generationparticipants born outside of Japan must have two parents and four grandparents bornin Japan of full Japanese descent. All participants must maintain a typical Japaneselifestyle, including consuming a typical Japanese diet.
Exclusion
Exclusion Criteria:
Part 1 (Groups 1-4), Part 2 and Part 3: History of any clinically significantneurological, respiratory (except mild asthma as a child), endocrine, metabolic,renal, hepatic, gastrointestinal, hematologic or psychiatric disease or disorder, orany uncontrolled medical illness.
History of suicidal ideation within one year prior to study drug administration asevidenced by answering "yes" to questions 4 or 5 on the suicidal ideation portion ofthe Columbia Suicide Severity Rating Scale (C-SSRS) completed at Screening, or anyhistory of suicide attempts within the last two years.
Study Design
Connect with a study center
CenExel ACT- Anaheim Clinical Trials /ID# 276423
Anaheim, California 92801
United StatesSite Not Available
CenExel ACT- Anaheim Clinical Trials /ID# 276423
Anaheim 5323810, California 5332921 92801
United StatesSite Not Available
Acpru /Id# 270552
Grayslake, Illinois 60030
United StatesSite Not Available
Acpru /Id# 270552
Grayslake 4894465, Illinois 4896861 60030
United StatesSite Not Available
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