Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma

Inclusion Criteria:

• 1: Clinical diagnosis of head and neck squamous cell carcinoma (stage I-IVA),without prior treatment, and planning to undergo either surgical treatment alone orsurgical treatment combined with chemotherapy and immunotherapy.

2: Ability to speak Chinese and possess basic reading and writing skills.

Exclusion Criteria:

• 1: Presence of mental illnesses such as dementia or delirium.

2: Active use of narcotic drugs, including consuming alcohol more than 4 times perday or more than 4 times per week.

3: Patients who alter their treatment plan during the course of treatment.

4: Current or prior use of antidepressants.