Associative Peripheral Stimulation for Reduction of Motor Impairment During Acute Period of Stroke Recovery

Inclusion Criteria:

1. Confirmed ischemic or hemorrhagic stroke no earlier than 7 days prior to enrollment;

2. Presentation of hemiparesis or paralysis of the upper extremity due to stroke;

3. Ability to comprehend and follow study instructions;

4. Ability to initiate finger extension (≥3°) at least three times per minute;

5. Fugl-Meyer Assessment (Upper Extremity) score of <47.

Exclusion Criteria:

1. Contraindications, intolerance, or high sensitivity to the experimental protocol;

2. History of upper-extremity disability prior to the index stroke;

3. Neurological conditions (other than stroke) affecting motor function;

4. Treatment of spasticity/increased tone in the affected upper extremity (e.g., withBotox injection);

5. Lack of access to a safe and suitable place of discharge for experimental sessionsand follow-up visits.