Outcomes of PFA Vs. RFA for Patients with PSVT: a Retrospective and Propensity Score Matching Study

Last updated: October 22, 2024
Sponsor: Caijie Shen
Overall Status: Active - Recruiting

Phase

N/A

Condition

Heart Defect

Arrhythmia

Fast Heart Rate (Tachycardia)

Treatment

Focal Radiofrequecy Ablation (RFA)

Focal Pulsed Field Ablation (PFA)

Clinical Study ID

NCT06573853
775050
  • Ages 18-80
  • All Genders

Study Summary

The goal of this retrospective study is to compare the long-term follow-up outcomes of pulses field ablation (PFA) Vs. radiofrequency ablation (RFA) for the patients with paroxysmal supraventricular tachycardia (PSVT). The main question to answer is:

Does the PFA was more effecient and safer that RFA for treatment of PSVT during procedure and after 1-year follow-up? Researchers will compare the acute and long-term efficiency and safety between PFA and RFA.

  1. Recieved PFA or RFA 1 year ago

  2. Finish the visit to the clinic at 1, 3, 6, 12 months for examinations and blood testings

  3. Patients recieved PFA and PFA under propensity matched comparison according to differen variety of PSVT

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients with symptomatic PSVT including: atrioventricular nodal re-entranttachycardia (AVNRT), atrioventricular re-entrant tachycardia (AVRT);

  2. Age range: 18 years old ≤ age ≤ 80 years old, with no gender restriction;

  3. Willing to receive the examinations and testings during one year follow-up requiredby the protocol;

  4. Voluntary signed informed consent.

Exclusion

Exclusion Criteria:

  1. Organic heart disease;

  2. History of cardiac surgery;

  3. Previous failed ablation of PSVT;

  4. Presence of any implants, such as a permanent pacemaker;

  5. Patients with invasive systemic infections or advanced malignant tumors;

  6. Contraindications for septal puncture or retrograde transaortic access surgery;

  7. Any condition that makes the use of heparin or aspirin inappropriate;

  8. Pregnant or lactating women;

  9. Inability to fully comply with the study procedures and follow-ups or to providetheir own informed consent;

  10. Coexistence with other arrhythmias, such as atrial fibrillation.

Study Design

Total Participants: 428
Treatment Group(s): 2
Primary Treatment: Focal Radiofrequecy Ablation (RFA)
Phase:
Study Start date:
October 11, 2022
Estimated Completion Date:
June 30, 2025

Study Description

The goal of this retrospective study is to compare the long-term follow-up outcomes of PFA Vs. RFA for the patients with PSVT. The main question to answer is:

Does the PFA was more effecient and safer that RFA for treatment of PSVT during procedure and after 1-year follow-up? Researchers will compare the acute and long-term efficiency and safety between PFA and RFA.

Connect with a study center

  • the First Affiliated Hospital of Ningbo University

    Ningbo, Zhejiang 315000
    China

    Active - Recruiting

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