Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors

Last updated: January 6, 2026
Sponsor: University of North Carolina, Chapel Hill
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Panic Disorders

Post-traumatic Stress Disorders

Anxiety Disorders

Treatment

Unemotional Writing

Written Exposure Therapy

Clinical Study ID

NCT06571513
22-1437
  • Ages > 18
  • Female
  • Accepts Healthy Volunteers

Study Summary

The main objective of this pilot trial is to determine the feasibility and initial efficacy of telehealth-delivered written exposure therapy to reduce the development of posttraumatic stress disorder after sexual assault. This pilot trial will provide the data necessary to design and support a large-scale trial.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Cisgender woman

  • Writes and speaks English

  • 18+ years of age

  • Presents for SANE care within 7 days of sexual assault

  • Discharged home after SANE care

  • Has an email address

  • Has an Apple (iOS) or Android-compatible smartphone with photo capability (forwriting session upload), without loss of cellular connection due to inability to paybill for >1 year

  • Willing to participate in remote therapy sessions

  • Meets PTSD risk score criteria

  • Meets with research assistant (RA) for informed consent within 30 days of SANE care

Exclusion

Exclusion Criteria:

  • Age <18

  • Pregnant

  • Incarcerated or in police custody

  • Presented for SANE care >7 days after assault

  • Has had a change in psychiatric medication regimen 1 month prior to study enrollment

  • Currently receiving cognitive-behavioral therapy or exposure-based psychologicaltreatment

  • Sexually assaulted at work or by a colleague

  • Currently lives with the person who assaulted them

  • History or condition that in investigator's judgment would likely make a participantnon-compliant/unsuitable for participation, including deafness or blindness

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: Unemotional Writing
Phase:
Study Start date:
September 23, 2024
Estimated Completion Date:
March 31, 2026

Study Description

Each year, approximately 100,000 women in the United States present to sexual assault nurse examiner (SANE) programs for evaluation after experiencing sexual assault. A wealth of data demonstrates that the development of adverse posttraumatic neuropsychiatric sequelae such as posttraumatic stress disorder (PTSD) is common in this population and that individuals with a history of traumatic stress exposure and/or posttraumatic stress symptoms are at increased risk. Unfortunately, no secondary preventive interventions are currently widely available that can prevent PTSD among those at high risk. Moreover, the 10% of sexual assault survivors in the United States who live in rural communities face even greater barriers to obtaining care. Written exposure therapy is an evidence-based, low-cost intervention that has demonstrated efficacy in treating chronic PTSD symptoms after a variety of traumatic stress exposures, including sexual assault. In addition, telehealth delivery of written exposure therapy for PTSD has yielded similar treatment outcomes and lower attrition compared to in-person delivery. The present protocol will assess the feasibility and preliminary efficacy of telehealth-delivered written exposure therapy as a secondary preventive intervention for sexual assault survivors in the acute aftermath of trauma exposure. This pilot trial will randomize N=80 women who received SANE care following sexual assault to five sessions of either virtual written exposure therapy (n=40) or virtual unemotional writing control (n=40). The same experienced therapists will deliver both interventions via telehealth/video sessions. Participant follow-ups will be performed remotely via REDCap self-report surveys by trained assessors and research associates. Results of this trial will demonstrate the feasibility and potential efficacy of written exposure therapy to reduce the development of PTSD after sexual assault and will provide the data necessary to design and support a large-scale trial.

Connect with a study center

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina 27516
    United States

    Site Not Available

  • University of North Carolina at Chapel Hill

    Chapel Hill 4460162, North Carolina 4482348 27516
    United States

    Site Not Available

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