Risk of Nerve Damage After Administration of Local Anesthesia

Last updated: August 23, 2024
Sponsor: Cleveland Dental Institute
Overall Status: Active - Recruiting

Phase

1

Condition

N/A

Treatment

4% Articaine with 1:200,000 epinephrine

2% lidocaine with 1:100,000 epinephrine

Clinical Study ID

NCT06564987
CDIOS0005
  • Ages 18-55
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This research aims to evaluate of the risk of nerve damage following the administration of articaine 4% and lidocaine 2% for Inferior Alveolar nerve Block (IANB). A Randomized Controlled Clinical Trial will be conducted where the patient will be randomly assigned to one the two groups; articaine 4% and Lidocaine 2%. The type of LA will be concealed to the operator, investigators and assessors. The patients will be monitored for any aigns of nerve parathesia for 3 months after the procedure.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with age between 18-55 years old

  • Patients need IANB

  • healthy patient

Exclusion

Exclusion Criteria:

  • medical conditions

  • allergies

  • medications

  • pregnancy and breastfeeding

  • inability to provide informed consent

  • specific dental or medical history.

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: 4% Articaine with 1:200,000 epinephrine
Phase: 1
Study Start date:
January 01, 2024
Estimated Completion Date:
March 31, 2025

Connect with a study center

  • Cleveland Dental Institute

    Akron, Ohio 44703
    United States

    Active - Recruiting

  • Cleveland Dental Institute

    Ashtabula, Ohio 44004
    United States

    Site Not Available

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