STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade

Last updated: November 22, 2024
Sponsor: Children's Hospital Medical Center, Cincinnati
Overall Status: Active - Recruiting

Phase

N/A

Condition

Asperger's Disorder

Williams Syndrome

Treatment

PEERS-T

STRW-T

Clinical Study ID

NCT06552286
CIN-DUNCAN-2023-0476
1R01HD113529-01
  • Ages 15-21
  • All Genders

Study Summary

The current study seeks to compare outcomes of a telehealth intervention targeting daily living skills (Surviving and Thriving in the Real World - Telehealth, or STRW-T) intervention to a control group telehealth intervention targeting social skills (Program for the Education and Enrichment of Relational Skills- Telehealth, or PEERS-T). The key endpoint will be change in daily living skills on primary and secondary outcome measures at the end of treatment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • in the last 2 years of high school, or deferring graduation

  • diagnosis of ASD based on clinical judgement and/or meeting the cut-off score on theAutism Diagnostic Observation Schedule, 2nd Edition

  • full scale IQ of 70 or above as measured by the Wechsler Abbreviated Scale ofIntelligence, 2nd Edition

  • deficient Daily Living Skills as assessed by the Vineland Adaptive Behavior Scales, 3rd Edition - at least 1 of the 3 Daily Living Skills subdomains is at least 15points below their full scale IQ

Exclusion

Exclusion Criteria:

  • significant aggressive behaviors or mental health issues that require treatment outof the scope of the current intervention.

  • if the adolescent has already completed the social skills group (PEERS), either atCincinnati Children's or in another setting, unless it has been a significant amountof time since they did the PEERS group (2-3 years, or up to the discretion of thePI).

Study Design

Total Participants: 192
Treatment Group(s): 2
Primary Treatment: PEERS-T
Phase:
Study Start date:
July 10, 2024
Estimated Completion Date:
December 31, 2029

Study Description

Individuals with high functioning autism spectrum disorder (ASD) are not developing the skills necessary to successfully transition from adolescence to college, employment, and independent living.

Daily living skills (DLS) have been linked to positive adult outcome in individuals with ASD.

Despite the importance of daily living skills to adult outcome, adolescents with high functioning ASD have impaired daily living skills.

A complex set of environmental, individual, and family factors likely affect the ability of adolescents with high functioning ASD to acquire critical daily living skills.

There are currently no evidence-based daily living skills intervention packages for adolescents with high functioning ASD that would prepare them for independence in adulthood.

A total of 192 autistic adolescents between the ages of 15-21 who are in their last 2 years of high school will be randomized to the STRW-T group (n=96) or the PEERS-T control group (n=96). Outcome measures will be assessed at baseline, post-treatment, 6-month follow-up, and 6-month post-high school graduation assessments. Adolescents will meet the following inclusion criteria: (1) a diagnosis of ASD; (2) enrolled in 11th or 12th grade; (3) Intelligence Quotient of greater than or equal to 70; and (4) a DLS deficit on the Vineland-3 interview as reported by caregivers.

Aim 1: Examine the efficacy of STRW-T on DLS compared to a control group (PEERS-T). Hypothesis 1: STRW-T youth will have greater gains on the primary DLS assessment (VABS-3) compared to PEERS-T youth at post-treatment; Hypothesis 2: STRW-T youth will have greater gains on secondary DLS assessments (Adaptive Behavior Assessment System, 3rd Edition, DLS-Goal Attainment Scale, daily phone diaries) compared to PEERS-T at post-treatment.

Aim 2: Evaluate whether the improvement on DLS outcomes by STRW-T are sustained beyond the intervention period. Hypothesis 3: The impact of STRW-T on DLS gains (as assessed by primary and secondary DLS assessments) will be sustained at 6-months post-treatment.

Aim 3: Examine the effects of the STRW-T intervention on outcomes in college, employment, and Quality of Life after high school graduation. Hypothesis 4: STRW-T youth will have better college, employment, and Quality of Life outcomes compared to PEERS-T youth at 6-months post-high school graduation.

Connect with a study center

  • University of North Carolina - Chapel Hill

    Carrboro, North Carolina 27510
    United States

    Active - Recruiting

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio 45229
    United States

    Active - Recruiting

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