Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder

Last updated: June 3, 2026
Sponsor: Knoa Pharma LLC
Overall Status: Completed

Phase

2

Condition

Addictions

Alcohol Dependence

Alcohol Use Disorder

Treatment

Placebo to match sunobinop

Sunobinop

Clinical Study ID

NCT06545916
SUN2003A
2024-517105-85-00
  • Ages > 18
  • All Genders

Study Summary

The purpose of this study is to evaluate the efficacy of sunobinop compared to placebo on alcohol consumption in subjects with alcohol use disorder.

Eligibility Criteria

Inclusion

Key Inclusion Criteria include:

  • Male and female age ≥18 years.

  • Diagnosis of moderate or severe alcohol use disorder.

  • Currently seeking treatment for alcohol use disorder.

  • Has 4 or more heavy drinking days (HDD) in each of the 4 weeks prior to baseline visit.

Key Exclusion Criteria include:

  • Subjects that meet current DSM-5 criteria for moderate or severe substance use disorder other than alcohol and nicotine.

Other protocol-specific inclusion and exclusion criteria may apply.

Study Design

Total Participants: 209
Treatment Group(s): 2
Primary Treatment: Placebo to match sunobinop
Phase: 2
Study Start date:
October 14, 2024
Estimated Completion Date:
May 05, 2026

Connect with a study center

  • Bio Terra Med SRL

    Bucharest, 010701
    Romania

    Site Not Available

  • Cabinet Medical Individual Dr. Andreea Popa

    Bucharest, 050802
    Romania

    Site Not Available

  • Spitalul Universitar De Urgenta Militar Central "Dr. Carol Davila"

    Bucharest, 010825
    Romania

    Site Not Available

  • Cabinet Medical Individual Dr. Andreea Popa

    Bucharest 683506, 050802
    Romania

    Active - Recruiting

  • Spitalul Universitar De Urgenta Militar Central "Dr. Carol Davila"

    Bucharest 683506, 010825
    Romania

    Active - Recruiting

  • Belmont Medical Office

    Brooklyn, New York 11212
    United States

    Site Not Available

  • Ohio Clinical Trials

    Columbus, Ohio 43212
    United States

    Site Not Available

  • Inquest Clinical Research

    Baytown, Texas 77521
    United States

    Site Not Available

  • Cebis Usa, Llc

    Houston, Texas 77074
    United States

    Site Not Available

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