Effect of Prophylactic Application of 40Hz Transcranial Stimulation in AICU on Incidence of Postoperative Delirium in Elderly Patients Undergoing Elective Gastrointestinal Surgery

Last updated: October 24, 2024
Sponsor: Henan Provincial People's Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anesthesia

Dementia

Aging

Treatment

40Hz stimulation

Clinical Study ID

NCT06542978
Henan FYX
  • Ages > 65
  • All Genders

Study Summary

Postoperative delirium is an acute central nervous system dysfunction caused by surgical stress, which is manifested by postoperative acute, non-specific changes in consciousness level, attention, cognitive ability and disturbance of sleep and wake cycles. It is one of the most common surgical complications in the elderly, occurring in more than 75% of patients receiving mechanical ventilation in the intensive care unit(ICU).Exogenous 40 Hz stimulation can improve cognitive functioning.Therefore, the aim of this study was to investigate the effect of exogenous 40Hz stimulation on the incidence of postoperative delirium in elderly patients undergoing elective gastrointestinal surgery in AICU.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 1.Age ≥ 65 years old,gender not limited

  • 2.ASA classification Ⅱ ~ Ⅳ

  • 3.Elective gastrointestinal general anesthesia surgery

Exclusion

Exclusion Criteria:

  • 1.History of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis

  • 2.Pre-operative coma, severe dementia, speech impairment or severe illnessincapacitated and unable to communicate

  • 3.Delirium on admission or pre-operative delirium, brain injury

  • 4.Severely infected person

  • 5.Severe liver dysfunction (Child-Pugh C), severe renal insufficiency (preoperativedialysis)

  • 6.Severe hearing or vision impairment

Study Design

Total Participants: 98
Treatment Group(s): 1
Primary Treatment: 40Hz stimulation
Phase:
Study Start date:
May 01, 2024
Estimated Completion Date:
March 01, 2025

Connect with a study center

  • Henan People's Hospital

    Zhengzhou, Henan
    China

    Active - Recruiting

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