Investigation of MP Pollution in the Human Respiratory System and Its Relationship to Lung Cancer

Last updated: May 6, 2025
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Overall Status: Active - Recruiting

Phase

N/A

Condition

Non-small Cell Lung Cancer

Cancer

Lung Cancer

Treatment

Bronchoalveolar Lavage (BAL) during Bronchoscopy

Clinical Study ID

NCT06530615
MCC-22605
  • Ages > 18
  • All Genders

Study Summary

This project will study and characterize Microplastic (MP) burden in the lungs of patients undergoing Bronchoalveolar Levage (BAL) in thoracic clinics at Moffitt.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • English or Spanish-speaking patients scheduled for bronchoscopy/bronchoalveolarlavage (BAL) in thoracic clinics at Moffitt.

Exclusion

Exclusion Criteria:

  • Patients with a known prior history of lung cancer or that have undergone aBronchoalveolar Lavage (BAL) procedure at any time in the past in the involved lungtargeted for BAL.

  • Patients that have had any prior lung or thoracic or surgeries or procedures (examples: removal of lung or portions of the involved lung (lobectomy,pneumonectomy, wedge resection/segmentectomy).

  • Patients with specimens that are considered to be non-adequate as trueBronchoalveolar Lavage Fluid (BALF) (i.e., absence of alveolar macrophages) afterpathologist's evaluation will be excluded from the study.

Study Design

Total Participants: 300
Treatment Group(s): 1
Primary Treatment: Bronchoalveolar Lavage (BAL) during Bronchoscopy
Phase:
Study Start date:
February 05, 2024
Estimated Completion Date:
July 31, 2026

Connect with a study center

  • Moffitt Cancer Center

    Tampa, Florida 33612
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.