Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1

Inclusion Criteria:

• A current diagnosis of social anxiety disorder as defined in the DSM-5.

• A Liebowitz Social Anxiety Scale total score of ≥60.

• Suitable contraception use in line with protocol requirements.

• Ability to swallow tablets.

Exclusion Criteria:

• History of bipolar disorder, schizophrenia, schizoaffective disorder, psychoticdisorders, anorexia or bulimia, body dysmorphic disorder, PTSD, autism-spectrumdisorder or obsessive-compulsive disorder, or any other Axis I or II disorder whichis currently the primary focus of treatment over social anxiety disorder.

• Hamilton Rating Scale for Depression score of ≥18.

• Moderate or severe alcohol-use disorder, or any other substance-use disorder (anyseverity) in the past 12 months.

• Use of psychotropic medications within 30 days of screening. Daily use ofbenzodiazepines within 90 days of screening.

• Any clinically significant medical history or findings as determined by theInvestigator that could interfere with the objectives of the study or put theparticipant at risk.