Tributyrin: Time Course & Efficacy to Improve Health & Performance

Last updated: April 10, 2025
Sponsor: Florida State University
Overall Status: Terminated

Phase

N/A

Condition

Inflammation

Treatment

Placebo

CoreBiome

Clinical Study ID

NCT06501898
STUDY00004764
  • Ages 30-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to determine if tributyrin supplementation improves metabolite concentrations, overall health biomarkers, and performance in sedentary men and women. The study would further understand the potential usage of tributyrin as a health and performance increasing supplement through improving gut and immune health, sleep, and performance as well as reduce inflammation. Participants will supplement for tributyrin for 4 weeks and complete fecal metabolite measures, cardiovascular evaluation, sleep assessment, and exercise testing as well as provide blood samples.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age: 30-50 years

  • Sedentary (<150 minutes of aerobic exercise per week)

Exclusion

Exclusion Criteria:

  • Chronic, uncontrolled metabolic, cardiovascular, gastrointestinal, or hepaticdisease

  • Consumption of supplements known to impact the microbiome, hydration status, coretemperature, or exercise performance

  • Experienced previous heat illness

  • Known injuries that limit exercise

  • BMI ≥ 40 kg/m^2

  • Pregnant

Study Design

Total Participants: 4
Treatment Group(s): 2
Primary Treatment: Placebo
Phase:
Study Start date:
August 19, 2024
Estimated Completion Date:
March 01, 2025

Connect with a study center

  • Institute of Sports Sciences & Medicine

    Tallahassee, Florida 32301
    United States

    Site Not Available

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