Optimization of the Skin Test Procedure With Iodinated Contrast Products for Certain Patients Suspected of Immediate Hypersensitivity

Last updated: July 4, 2024
Sponsor: University Hospital, Strasbourg, France
Overall Status: Active - Recruiting

Phase

N/A

Condition

Allergies & Asthma

Allergy

Allergy (Pediatric)

Treatment

N/A

Clinical Study ID

NCT06498219
9025
  • Ages > 18
  • All Genders

Study Summary

Hypersensitivity to iodinated contrast products (ICP) affects 1 to 3% of injected patients. These reactions require an allergological assessment with skin tests in order to distinguish allergic immunological mechanisms from other non-specific mechanisms. Current recommendations recommend carrying out prick tests followed by intradermal reactions up to a 10th dilution. However, undiluted IDRs are carried out by several teams under certain conditions, without this having been validated. Experience tends to show that these IDRs are relevant in certain patients to make the diagnosis without risk.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Major subject (≥18 years old)

  • Subject treated in the allergology department in the period from June 1, 2020 toJuly 3, 2023 for suspected allergic hypersensitivity to ICPs and having had at leastone undiluted intradermal reaction to one or more ICPs.

  • Absence of written opposition in the medical file of the subject (and/or their legalrepresentative if applicable) to the reuse of their data for scientific researchpurposes.

Exclusion

Exclusion Criteria:

  • Presence of opposition from the subject (and/or their legal representative ifapplicable) to the reuse of their data for scientific research purposes.

Study Design

Total Participants: 100
Study Start date:
December 21, 2023
Estimated Completion Date:
December 31, 2024

Connect with a study center

  • Service de Pneumologie - CHU de Strasbourg - France

    Strasbourg, 67091
    France

    Active - Recruiting

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