The Optimal Timing of the Initiation of Esophagogastroduodenoscopy After Oral Lidocaine Spray

Last updated: July 9, 2024
Sponsor: National Cheng-Kung University Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Fast Heart Rate (Tachycardia)

Heart Disease

Cardiac Disease

Treatment

Lidocaine

Clinical Study ID

NCT06497296
B-ER-111-218
  • Ages 20-90
  • All Genders

Study Summary

Esophagogastroduodenoscopy (EGD) is the main examination in the upper gastrointestinal field. Aspiration pneumonia may happen if choking occurs during the EGD insertion, and the exam quality and efficacy may be affected if gag reflex occurs. The endoscopist may terminate the exam to avoid complications if the patient could not obey the orders. To reach the high quality of EGD examination and to avoid possible complications, the patient's comfort and compliance during the EGD examination are important. Sedation using propofol can improve the patient's comfort and compliance. However, in patients unsuitable for systemic anesthesia, local lidocaine spray at pharynx is performed instead. Until now, there is no standardization of the waiting time between lidocaine spray and the initiation of EGD. This study aimed to investigate the optimal timing of the initiation of esophagogastroduodenoscopy after lidocaine spray.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Eligible participants included patients aged ≥ 20 years who scheduled EGD from OPDfor dyspepsia, peptic ulcer disease, GERD, subepithelial lesion evaluation, anddiarrhea

Exclusion

Exclusion Criteria:

  • GI bleeding

  • endoscopic submucosal dissection due to prolonged scheduled procedure time

  • patients from emergency department or ward

Study Design

Total Participants: 160
Treatment Group(s): 1
Primary Treatment: Lidocaine
Phase:
Study Start date:
January 01, 2023
Estimated Completion Date:
December 31, 2024

Study Description

This study compares the 1-minute waiting time and 3-minute waiting time between the lidocaine spray and the EGD initiation. During the topical anesthesia stage, investigators give local spray with 6 puff on pharynx at the 0 minute in both groups. After the waiting time, EGD is inserted.

The baseline heart rate and blood pressure were recorded before EGD and during the EGD passing through pharynx respectively. After the whole procedure, enrolled patients will fill in the EGD quality questionnaire.

Through this study, investigators can figure out whether 1 minute or 3 minutes may be the optimal waiting time after lidocaine spray.

Connect with a study center

  • Hsueh-Chien Chiang

    Tainan, Other (Non U.s.) 704
    Taiwan

    Active - Recruiting

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