A Study in Patients With Mixed Dyslipidemia

Inclusion Criteria:

1. Must have given written informed consent and be able to comply with all studyrequirements.

2. Males or females aged 18 to 75 aged years, inclusive, at the time of informedconsent

3. Fasting LDL-C ≥ 70 mg/dL [1.8 mmol/L] at Screening.

4.150 mg/dL [1.7 mmol/L] ≤ fasting TG < 500 mg/dL [5.6 mmol/L] at Screening, which may be repeated once if deemed necessary.

5.On a stable statin for at least 1 month before Screening and plan to remain on the same medication and dose for the duration of the study.

6.Females must be non-pregnant and non-lactating, and either surgically sterile or post-menopausal 7.Male patients agreeing to use acceptable methods of contraception

Exclusion Criteria:

1. Active pancreatitis within 12 weeks prior to Day 1.

2. Clinically significant acute cardiovascular even or procedure

3. HbA1c > 9.0% at Screening or patients with diabetes who have experienced diabeticketoacidosis, diabetic decompensation, hyperosmolar hyperglycemic nonketotic coma,diabetes complications, recurrent infections, or hospitalization related to poorglycemic control within 24 weeks prior to Day 1.

4. Presence of any clinically significant uncontrolled disease known to influence serumlipids or lipoproteins. NOTE: Patients on thyroid replacement therapy are eligibleif the dosage of thyroxine has been stable for at least 12 weeks prior to Day 1.

5. Use of TG lowering medication , non-prescription dietary supplements or othercholesterol lowering medication 30 days prior to Day 1, other than statins andezetimibe.