Efficacy and Safety of VDS+SU in the Treatment of OAB-dry in Children

Inclusion Criteria:

1. Children older than 5 years who were admitted to the Department of Urology,Children's Hospital Affiliated to Chongqing Medical University and diagnosed withdry OAB.

2. The results of our laboratory indicated that the serum vitamin D level was lowerthan 35ng/mL.

3. The child (guardian) has been informed of the nature of the study, understands theprovisions in the protocol, is able to guarantee compliance, and signs the informedconsent.

Exclusion Criteria:

1. Patients with other urinary system malformations or serious diseases (such ashypospadias, cryptorchidism, posterior urethral valvular disease, vesicoureteralreflux, neurogenic bladder, urinary system tumors, urinary calculi, bladder andurethral injuries, etc.);

2. complicated with neurological diseases (such as epilepsy, spinal cord injury, spinalcord dysplasia, tethered cord syndrome, multiple sclerosis, autism spectrumdisorder, etc.);

3. Patients with severe heart disease, abnormal liver and kidney function, lungdisease, bone malformation, severe digestive tract disease, and genetic metabolicdisease;

4. History of gastrointestinal surgery and urinary system surgery;

5. Dry stool, long-term constipation;

6. are taking anticonvulsant and antiepileptic drugs, hormones, antituberculosis drugs;

7. Previous history of hypercalcemia, hyperphosphatemia with renal rickets;

8. History of unexplained hematuria and urinary tract infection in the past 1 year;

9. Have a history of allergy or allergic reaction to vitamin D preparations;

10. Participating in another clinical study at the time of visit or during the follow-upof another clinical study;

11. Those who did not want to participate in the study or had poor follow-up compliance