Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures

Last updated: March 2, 2026
Sponsor: Acorn Biolabs Inc.
Overall Status: Active - Recruiting

Phase

N/A

Condition

Hives (Urticaria)

Rash

Skin Wounds

Treatment

N/A

Clinical Study ID

NCT06477172
ACN-101
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male and Female

  • Ages: 18-60

  • Any Fitzpatrick skin type

  • Planning a medical aesthetic procedure

  • For subjects receiving hair procedures (closed to enrollment):

  1. Androgenic alopecia

  2. Traction alopecia

  3. Scarring alopecia

  4. Stable use of any medication or supplement for hair loss, includingfinasteride, any other 5 α-reductase inhibitor, minoxidil, steroids, orhormonal products, during the 3 months prior to enrollment in the study isallowed.

  5. No intention to start new hair growth medications or change dose of hair growthmedications from the time of consent through the end of the study follow-upperiod.

  • Undergoing one of the following medical aesthetic procedures:
  1. Laser resurfacing of the face (ablative or non-ablative) or Ellacor of the face (Ellacor closed to enrollment)

  2. Tixel of the face

  3. Keralase of the scalp (scalp treatment closed to enrollment)

  4. Acne Scars and Surgery scars, either old or new as long as old scars are alsobeing treated with ablative or non-ablative laser or microneedling (e.g.abdominoplasty, breast reduction/ reconstruction/enhancement, post-weight loss,etc.

  • Planning to use Acorn Autologous Hair Follicle Secretome cosmetic product

Exclusion

Exclusion Criteria:

  • Pregnant or Breastfeeding

  • Participation in an interventional clinical trial in the last 30 days

  • Use of other topical cosmetic products that may confound results

  • Use of retinoids within 7 days prior to facial procedure

  • For those receiving hair treatment, must not have had a hair transplant in thetreatment area within the past 12 months

  • Any health condition that in the investigator's opinion should precludeparticipation in study

Study Design

Total Participants: 500
Study Start date:
September 09, 2024
Estimated Completion Date:
February 28, 2027

Study Description

This non-interventional, observation study is to collect real-world data on the use of an autologous, hair follicle derived secretome topical cosmetic product following various medical aesthetic procedures.

Connect with a study center

  • Dr. Jean Carruthers Cosmedic

    Vancouver, British Columbia V5Z 4E1
    Canada

    Active - Recruiting

  • Dr. Amber Bocknek

    Aurora, Ontario L4G1B9
    Canada

    Active - Recruiting

  • Sanjeev Goel MD Peak Human

    Brampton, Ontario L6W 3E1
    Canada

    Completed

  • BeSpoke Wellness

    Toronto, Ontario
    Canada

    Completed

  • Compass Dermatology

    Toronto, Ontario M4S 2N5
    Canada

    Site Not Available

  • Dr. Nowell Solish Cosmetic Dermatologist

    Toronto, Ontario M5R 3N8
    Canada

    Active - Recruiting

  • FCP Dermatology

    Toronto, Ontario M5X 1A9
    Canada

    Site Not Available

  • Rejuuv

    Toronto, Ontario M5R 0C7
    Canada

    Active - Recruiting

  • The Toronto Hair Transplant Clinic

    Toronto, Ontario MAY 2P2
    Canada

    Site Not Available

  • BeSpoke Wellness

    Toronto 6167865, Ontario 6093943
    Canada

    Completed

  • Dr. Nowell Solish Cosmetic Dermatologist

    Toronto 6167865, Ontario 6093943 M5R 3N8
    Canada

    Active - Recruiting

  • FCP Dermatology

    Toronto 6167865, Ontario 6093943 M5X 1A9
    Canada

    Site Not Available

  • Rejuuv

    Toronto 6167865, Ontario 6093943 M5R 0C7
    Canada

    Active - Recruiting

  • The Toronto Hair Transplant Clinic

    Toronto 6167865, Ontario 6093943 MAY 2P2
    Canada

    Site Not Available

  • Clinique Antiaging

    Montreal, Quebec H3A 1S2
    Canada

    Active - Recruiting

  • Skin Wellness Dermatology

    Birmingham, Alabama 35209
    United States

    Site Not Available

  • BelleSante

    Scottsdale, Arizona 85260
    United States

    Active - Recruiting

  • AM Facial Plastics

    Beverly Hills, California 90211
    United States

    Site Not Available

  • Arash Moradzadeh MD

    Beverly Hills, California 90210
    United States

    Site Not Available

  • Glenn Vallecillos, MD Inc

    Beverly Hills, California 90210
    United States

    Site Not Available

  • Jalalabadi Plastic Surgery

    Beverly Hills, California 90210
    United States

    Site Not Available

  • Behr Laser & Skin Care Center

    Fresno, California 93720
    United States

    Active - Recruiting

  • Aesthetics By Dr. Lee

    Granite Bay, California 95746
    United States

    Active - Recruiting

  • Carlo Honrado, MD, FACS

    Los Angeles, California 90067
    United States

    Active - Recruiting

  • Marcus Medical

    Manhattan Beach, California 90266
    United States

    Site Not Available

  • N2 Aesthetics

    Manhattan Beach, California 90266
    United States

    Active - Recruiting

  • Marina Plastic Surgery

    Marina del Rey, California 90292
    United States

    Active - Recruiting

  • M Beauty by Tess

    San Diego, California 92126
    United States

    Active - Recruiting

  • Modern Aesthetics

    Walnut Creek, California 94598
    United States

    Site Not Available

  • Dr. Christie

    West Hollywood, California 90069
    United States

    Completed

  • Ziering Medical

    West Hollywood, California 90069
    United States

    Active - Recruiting

  • Glenn Vallecillos, MD Inc

    Beverly Hills 5328041, California 5332921 90210
    United States

    Site Not Available

  • N2 Aesthetics

    Manhattan Beach 5370082, California 5332921 90266
    United States

    Active - Recruiting

  • Ziering Medical

    West Hollywood 5408076, California 5332921 90069
    United States

    Active - Recruiting

  • BEAUTY by BUFORD

    Lone Tree, Colorado 80124
    United States

    Completed

  • Bauman Medical

    Boca Raton, Florida 33432
    United States

    Active - Recruiting

  • Mirror Plastic Surgery

    St. Petersburg, Florida 33701
    United States

    Active - Recruiting

  • Hive Aesthetic LLC

    Chicago, Illinois 60657
    United States

    Active - Recruiting

  • Chernoff Cosmetic Surgery

    Indianapolis, Indiana 46220
    United States

    Active - Recruiting

  • ICON Antiaging & Aesthetics

    Birmingham, Michigan 48009
    United States

    Site Not Available

  • Davis Cosmetic Plastic Surgery

    Cherry Hill, New Jersey 08003
    United States

    Completed

  • AIEREM Aesthetics Spa & Plastic Surgery

    Manhattan, New York 75231
    United States

    Active - Recruiting

  • Lewis Dermatology and Associates

    New York, New York 10021
    United States

    Active - Recruiting

  • Luxurgery

    New York, New York 10021
    United States

    Active - Recruiting

  • Sadick Dermatology

    New York, New York 10075
    United States

    Site Not Available

  • SkinLabRx

    New York, New York 10028
    United States

    Completed

  • Unger Medical Hair Transplant Clinic

    New York, New York 10021
    United States

    Site Not Available

  • AIEREM Aesthetics Spa & Plastic Surgery

    Syosset, New York 11791
    United States

    Active - Recruiting

  • Haideh Hirmand MD, Aesthetic Plastic Surgery

    New York 5128581, New York 5128638 10028
    United States

    Active - Recruiting

  • Lewis Dermatology and Associates

    New York 5128581, New York 5128638 10021
    United States

    Active - Recruiting

  • Luxurgery

    New York 5128581, New York 5128638 10021
    United States

    Active - Recruiting

  • Sadick Dermatology

    New York 5128581, New York 5128638 10075
    United States

    Site Not Available

  • Unger Medical Hair Transplant Clinic

    New York 5128581, New York 5128638 10021
    United States

    Site Not Available

  • Austin Plastic Surgeon

    Austin, Texas 78758
    United States

    Active - Recruiting

  • Dallas Plastic Surgery Institute

    Dallas, Texas 75225
    United States

    Active - Recruiting

  • US Dermatology Partners / Dermatology Associates of Tyler

    Tyler, Texas 75703
    United States

    Active - Recruiting

  • AG Aesthetic Centre

    Vancouver, Washington 98660
    United States

    Active - Recruiting

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