Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery

Last updated: April 22, 2025
Sponsor: NYU Langone Health
Overall Status: Active - Recruiting

Phase

4

Condition

Prostate Disorders

Treatment

Magnesium sulfate

Clinical Study ID

NCT06477133
24-00463
  • Ages > 18
  • Male

Study Summary

The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain. Subjects will be randomized to receive magnesium or not receive it, as part of a standardized general anesthetic for prostate surgery. The primary objective is to demonstrate improved pain scores in patients receiving magnesium sulfate as an adjunctive analgesic during surgery. Secondary objectives include demonstrating reduced requirements for other opioids, reduced postoperative shivering, improved discharge home and adequate neuromuscular blockade reversal, measured by quantitative train of four monitoring.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age 18 and older.

  2. Undergoing a robotic prostatectomy under general anesthesia.

  3. Is willing and able to provide consent to participate in the study.

Exclusion

Exclusion Criteria:

  1. Patients younger than 18 years

  2. Patients with end-stage renal disease

  3. Known allergy to magnesium sulfate preparations

  4. Any patient that the investigators feel cannot comply with all study relatedprocedures

Study Design

Total Participants: 110
Treatment Group(s): 1
Primary Treatment: Magnesium sulfate
Phase: 4
Study Start date:
June 04, 2024
Estimated Completion Date:
June 30, 2026

Connect with a study center

  • NYU Langone Health

    New York, New York 10016
    United States

    Active - Recruiting

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