The Effects of L-arginine Supplementation on Anaerobic Exercise Performance

Last updated: June 25, 2024
Sponsor: University of Manitoba
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

L-arginine

Placebo

Clinical Study ID

NCT06475391
HE2024-0063
  • Ages 18-39
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Recreationally physically active individuals will be recruited for the study. Inthis context it means all participants perform 1-hour of exercise per day over 3-days per week at a minimum for 1-month. All participants will be between the agesof 18-39 years of age.

Exclusion

Exclusion Criteria:

  • Exclusion criteria for the study includes: 1) smokers; 2) unhealthy (havecardiovascular, metabolic, neurological, or psychological disease); 3) takingmedication for any condition; 4) any known allergy to the supplements of interest (L-arginine or placebo [dextrose]).

Study Design

Total Participants: 20
Treatment Group(s): 2
Primary Treatment: L-arginine
Phase:
Study Start date:
June 14, 2024
Estimated Completion Date:
December 31, 2024

Study Description

After being enrolled in the study you will be measured on a number of parameters including: body circumferences, body composition via bioelectrical impedance analysis (BIA), height, weight, resting blood pressure, and resting heart rate.

All participants will be asked to complete the same protocol for this study. The study design is a randomized, double-blind, placebo controlled, cross-over type of study. What this means is that each participant in the study will complete two exercise sessions after ingesting either a placebo (dextrose - a sugar molecule) or the active ingredient [insert supplement] plus dextrose. Neither you nor the research assistant testing you on the exercise sessions will know which ingredient you are ingesting before each exercise trial (i.e., the double-blind portion of the study). We will also randomize the order of which supplement plus placebo or placebo alone you will ingest so neither you nor the research assistant testing will know this either. The cross-over part of the study is that you will complete 2 testing sessions to assess some physical performance variables (grip strength, jump height and power, and anaerobic energy system power output) with one-week of a wash-out period between them. This will allow us to compare the placebo session to the active nutritional supplement plus placebo condition to evaluate if the supplements improve exercise performance acutely.

You will also be asked to fill in a 24-hour food and fluid log for the period before your initial exercise test. Then you will be asked to repeat this food and fluid intake when completing the second session. No caffeine, alcohol, or vigorous exercise will be allowed for the 24-hours prior to each trial.

Connect with a study center

  • Applied Research Centre; Active Living Centre

    Winnipeg, Manitoba R3T 2N2
    Canada

    Active - Recruiting

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