Functional Lumen Opening With Self-Forming Magnetic Anastomosis

Inclusion Criteria:

1. Aged 22 years or older at screening

2. Candidate for laparoscopic small bowel surgery requiring small bowel anastomosiswith cardiac/medical clearance for surgery

3. Able to understand and sign informed consent document

4. American Society of Anesthesiologists (ASA) score < IV at time of procedure

5. Lives, and intends to remain, within a 185-mile radius of study center for theduration of the study

6. Able to refrain from smoking during study follow-up period

Exclusion Criteria:

1. Known or suspected allergy to silicone, nickel, titanium or Nitinol

2. BMI > 55 kg/m2

3. Uncontrolled diabetes (defined as HbA1c >10%)

4. Congenital or acquired anomalies of the GI tract, including atresia or malrotation

5. Diagnosed with obstructed or perforated colon cancer

6. Any documented conditions for which endoscopy and/or laparoscopy would becontraindicated or history of previous technically difficult or failed endoscopy

7. Any previous major surgery on the stomach, duodenum, hepatobiliary tree (excludinglaparoscopically removed gallbladder or prior sleeve gastrectomy), pancreas or rightcolon

8. Coagulation deficiency not normalized by medical treatment or platelet count <50,000/µL

9. Known moderate to severe renal disease (eGFR < 44 milliliters per minute per 1.73m2)or ongoing dialysis

10. Hyperkalemia / hypercoagulability or prior Venus Thromboembolism / PulmonaryEmbolism

11. Immunocompromised (e.g., active treatment for malignancies, hematologic malignancy,on immunosuppressive therapy, moderate or severe primary immunodeficiency, advancedor untreated HIV, active treatment with high-dose corticosteroids (i.e., 20 or moremg of prednisone or equivalent per day when administered for 2 or more weeks priorto surgery) or other immunosuppressive or immunomodulatory agents

12. Active H. pylori infection

13. Active or suspected infection at the surgical site or a CDC Class 3/contaminated orClass 4/dirty-infected surgical wound.

14. Obstructive Sleep Apnea on CPAP unless assessed and cleared by independent physician

15. Contraindication to general anesthesia

16. Breast-feeding, pregnant, or planning on becoming pregnant during the follow-upperiod

17. Currently participating or has participated in another clinical trial within thepast 30 days and is receiving/has received an investigational drug, device, orbiologic agent

18. Subject is not appropriate for inclusion in the clinical trial, per the medicalopinion of the Principal Investigator