Phase
Condition
Congestive Heart Failure
Hyponatremia
Chest Pain
Treatment
Recompensation (guideline directed medical therapy)
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Patients with decompensated heart failure caused by heart failure irrespective ofejection fraction (heart failure with reduced, mildly reduced or preserved ejectionfraction and de-novo heart failure)
Signs of decompensation: peripheral edema, jugular venous distension, pulmonaryrales, protodiastolic gallop rhythm, ascites, or demonstration of pulmonary venouscongestion on chest X-ray
Previous documented beta blocker therapy
elevated natriuretic peptides (nt-pro-BNP ≥125 pg/ml)
patients admitted to the intensive care unit
Exclusion
Exclusion Criteria:
Left ventricular or biventricular assist device therapy
Cardiogenic shock
need of vasopressor (catechoalmines) therapy or other inotropic support (dobutamineor levosimendan)
Clinical symptomatic hypotension
Bradycardia (<50 bpm)
patients requiring dialysis (CVVHD)
Inflammatory bowel disease (eg, M. Crohn or Colitis ulcerosa)
Not able to give written informed consent
Study Design
Connect with a study center
Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital Saarland, Saarland University
Homburg, 66421
GermanySite Not Available
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