The Feasibility of a Radiological Score Based on CT Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia

Last updated: March 24, 2025
Sponsor: University of Tartu
Overall Status: Active - Recruiting

Phase

N/A

Condition

Occlusions

Treatment

N/A

Clinical Study ID

NCT06445660
03.01.2024
  • Ages > 18
  • All Genders

Study Summary

Computed tomography (CT) is the standard modality for scanning patients with critical acute abdominal conditions, including suspected acute mesenteric ischemia (AMI). CT imaging can potentially differentiate between reversible and irreversible ischaemic damage of the bowel. This moment is pivotal in selecting the treatment strategy for AMI - in the absence of irreversible damage; reperfusion therapy can preserve intestinal viability, thereby avoiding the need for bowel resection. The present study tests the hypothesis that combining several symptoms may enhance the diagnostic performance of CT scanning in detecting salvageable bowel in patients with AMI. This study is an ancillary component of the AMESI study (Clinical Trials: NCT05218863) - a prospective, multicentre observational study aimed at identifying the incidence and describing the outcomes of acute mesenteric ischemia (AMI) in adult hospitalized patients. The ultimate purpose of the present study is to create a computed tomography-based radiological score for the assessment of bowel viability in patients with AMI.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participant in AMESI study

  • confirmed or suspected acute mesenteric ischaemia

  • CT scan of the entire abdominal cavity / full body using intravenous contrast mediais available

Exclusion

Exclusion Criteria:

  • Scans without the use of an intravenous contrast media or those covering only apartial area of the abdomen will be excluded.

Study Design

Total Participants: 200
Study Start date:
June 06, 2022
Estimated Completion Date:
May 31, 2025

Connect with a study center

  • Tartu University Hospital

    Tartu, 50408
    Estonia

    Active - Recruiting

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