A Survey of Recombinant ADAMTS13 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

Last updated: October 2, 2025
Sponsor: Takeda
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Recombinant ADAMTS13

Clinical Study ID

NCT06441578
TAK-755-4005
jRCT2031240130
  • All Genders

Study Summary

This study is a survey in Japan of recombinant ADAMTS13 used to treat or to prevent participants with congenital thrombotic thrombocytopenic purpura (cTTP). The study sponsor will not be involved in how the participants are treated but will provide instructions on how the clinics will record what happens during the study.

The main aim of the study is to check for side effects related from recombinant ADAMTS13 and to check if recombinant ADAMTS13 improves or prevents cTTP.

During the study, participants with cTTP will take recombinant ADAMTS13 intravenous injection according to their clinic's standard practice. The study doctors will check for side effects from recombinant ADAMTS13 for 18 months.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All participants with congenital thrombotic thrombocytopenic purpura (cTTP), treated with recombinant ADAMTS13

Exclusion

Exclusion Criteria:

  • None

Study Design

Total Participants: 40
Treatment Group(s): 1
Primary Treatment: Recombinant ADAMTS13
Phase:
Study Start date:
May 30, 2024
Estimated Completion Date:
September 30, 2032

Connect with a study center

  • Takeda selected site

    Tokyo,
    Japan

    Site Not Available

  • Takeda selected site

    Tokyo 1850147,
    Japan

    Active - Recruiting

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