Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

Last updated: May 11, 2026
Sponsor: Hoffmann-La Roche
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Geographic Atrophy

Diabetic Macular Edema

Macular Degeneration

Treatment

Faricimab

Clinical Study ID

NCT06439576
ML45401
  • Ages > 18
  • All Genders

Study Summary

The Farseeing Study will explore long-term effectiveness, safety, and treatment patterns among patients being treated with faricimab in real-world, routine clinical practice in China. It is a primary data collection, non-interventional, prospective and retrospective, multi-center study designed to collect real-world, long-term data to gain clinical evidence on faricimab, by observing cohorts of patients with neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) who are receiving treatment with faricimab.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Have signed the informed consent

  2. Female and male Chinese patients, who had been diagnosed with nAMD, DME, or RVO byCFP, OCT, FFA, ICGA, or OCTA

  3. ≥50 years old for patients with nAMD, ≥18 years old both for patients with DME andRVO, at the time of signing informed consent (or the first administration offaricimab, whichever occurs first)

  4. Patients for whom the decision to receive treatment with faricimab is made prior toand independent from study participation

  5. Patients have received at least one faricimab treatment (the first dose) in thestudy eye

Exclusion

Exclusion Criteria:

  1. Patients not receiving treatment for nAMD/DME/RVO with faricimab according to thestandard of care and in line with the current summary of product characteristics (SPC) / labeling in China

  2. Active ocular inflammation or suspected / active ocular infection in either eye

  3. Received any other anti-VEGF treatment after faricimab

  4. Received any steroid treatment within 6 months (180 days) before the first faricimabtreatment in the study eye

  5. Any participation in any other clinical trials currently

  6. Patients could not provide the clinical data (visual acuity and OCT images) within 2weeks (14 days) before receiving the initial faricimab injection

Study Design

Total Participants: 1000
Treatment Group(s): 1
Primary Treatment: Faricimab
Phase:
Study Start date:
May 09, 2024
Estimated Completion Date:
November 15, 2027

Connect with a study center

  • Joint Shantou International Eye Center

    Shantou, Guangdong 515051
    China

    Site Not Available

  • Joint Shantou International Eye Center

    Shantou 1795940, Guangdong 1809935 515051
    China

    Site Not Available

  • The First Affiliated Hospital of Henan UN of Science and Technology

    Luoyang, Henan 471000
    China

    Site Not Available

  • The First Affiliated Hospital of Henan UN of Science and Technology

    Luoyang 1801792, Henan 1808520 471000
    China

    Site Not Available

  • Taihe Hospital of Shiyan

    Shiyan, Hubei 442000
    China

    Site Not Available

  • Taihe Hospital of Shiyan

    Shiyan 1794903, Hubei 1806949 442000
    China

    Site Not Available

  • Xuzhou No.1 Peoples Hospital

    Xuzhou, Jiangsu 221002
    China

    Site Not Available

  • Xuzhou No.1 Peoples Hospital

    Xuzhou 10630003, Jiangsu 1806260 221002
    China

    Site Not Available

  • Fushun Eye Hospital

    Fushun, Liaoning 110114
    China

    Site Not Available

  • Panjin Central Hospital

    Panjin, Liaoning 124010
    China

    Site Not Available

  • The First Hospital of China Medical University

    Shenyang, Liaoning 110001
    China

    Site Not Available

  • Fushun Eye Hospital

    Fushun 2037355, Liaoning 2036115 110114
    China

    Site Not Available

  • Panjin Central Hospital

    Panjin 10794003, Liaoning 2036115 124010
    China

    Site Not Available

  • The First Hospital of China Medical University

    Shenyang 2034937, Liaoning 2036115 110001
    China

    Active - Recruiting

  • Affiliated Hospital of Shandong Second Medical University

    Weifang, Shandong 261031
    China

    Site Not Available

  • Affiliated Hospital of Shandong Second Medical University

    Weifang 1791681, Shandong 1796328 261031
    China

    Site Not Available

  • Shanghai General Hospital

    Shanghai, Shanghai Municipality 200080
    China

    Site Not Available

  • Shanghai General Hospital

    Shanghai 1796236, Shanghai Municipality 1796231 200080
    China

    Active - Recruiting

  • The First People's Hospital of Chengdu

    Chengdu, Sichuan 610016
    China

    Site Not Available

  • The First People's Hospital of Chengdu

    Chengdu 1815286, Sichuan 1794299 610016
    China

    Active - Recruiting

  • The First People's Hospital of Kashgar

    Kashgar, Xinjiang Uygur 844000
    China

    Site Not Available

  • The First People's Hospital of Kashgar

    Kashgar 1280849, Xinjiang Uygur 844000
    China

    Site Not Available

  • The First People's Hospital of Yunnan Province

    Kunming, Yun'nan 650032
    China

    Site Not Available

  • The First People's Hospital of Yunnan Province

    Kunming 1804651, Yun'nan 650032
    China

    Site Not Available

  • Jinhua municipal central hospital

    Jinhua, Zhejiang 321083
    China

    Site Not Available

  • Jinhua municipal central hospital

    Jinhua 1805528, Zhejiang 1784764 321083
    China

    Site Not Available

  • Peking University People's Hospital

    Beijing, 100044
    China

    Site Not Available

  • Peking University People's Hospital

    Beijing 1816670, 100044
    China

    Site Not Available

  • Sichuan Provincial People's Hospital

    Chengdu, 610072
    China

    Site Not Available

  • Sichuan Provincial People's Hospital

    Chengdu 1815286, 610072
    China

    Site Not Available

  • People's Hospital of Dingzhou

    Dingzhou, 73000
    China

    Site Not Available

  • People's Hospital of Dingzhou

    Dingzhou 1812728, 73000
    China

    Site Not Available

  • Dongyang People's Hospital

    Dongyang, 322100
    China

    Site Not Available

  • Dongyang People's Hospital

    Dongyang 1791056, 322100
    China

    Site Not Available

  • Zhongshan Ophthalmic Center, Sun Yat-sen University

    Guangzhou, 510060
    China

    Site Not Available

  • Zhongshan Ophthalmic Center, Sun Yat-sen University

    Guangzhou 1809858, 510060
    China

    Site Not Available

  • Guizhou Provincial People's Hospital

    Guiyang, 550002
    China

    Site Not Available

  • Guizhou Provincial People's Hospital

    Guiyang 1809461, 550002
    China

    Site Not Available

  • Eye Hospital of Shandong First Medical University

    Jinan, 250021
    China

    Site Not Available

  • Eye Hospital of Shandong First Medical University

    Jinan 1805753, 250021
    China

    Site Not Available

  • The First Affiliated Hospital of Lanzhou University

    Lanzhou, 730000
    China

    Site Not Available

  • The First Affiliated Hospital of Lanzhou University

    Lanzhou 1804430, 730000
    China

    Site Not Available

  • The Affiliated Hospital of Southwest Medical University, Zhongshan Campus

    Luzhou,
    China

    Site Not Available

  • The Affiliated Hospital of Southwest Medical University, Zhongshan Campus

    Luzhou 1801640,
    China

    Site Not Available

  • Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University)

    Nanjing, 210029
    China

    Site Not Available

  • Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University)

    Nanjing 1799962, 210029
    China

    Site Not Available

  • The People?s Hospital of Guangxi Zhuang Autonomous Region

    Nanning, 530021
    China

    Site Not Available

  • The People?s Hospital of Guangxi Zhuang Autonomous Region

    Nanning 1799869, 530021
    China

    Site Not Available

  • Qingdao Eye Hospital of Shandong First Medical University

    Qingdao, 265299
    China

    Site Not Available

  • Qingdao Eye Hospital of Shandong First Medical University

    Qingdao 1797929, 265299
    China

    Site Not Available

  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    Shanghai, 200025
    China

    Site Not Available

  • Shanghai First People's Hospital

    Shanghai, 200080
    China

    Active - Recruiting

  • Shanghai Tenth People's Hospital

    Shanghai, 200072
    China

    Site Not Available

  • Shanghai Zhoupu Hospital

    Shanghai,
    China

    Site Not Available

  • Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    Shanghai, 200092
    China

    Site Not Available

  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    Shanghai 1796236, 200025
    China

    Active - Recruiting

  • Shanghai Tenth People's Hospital

    Shanghai 1796236, 200072
    China

    Site Not Available

  • Shanghai Zhoupu Hospital

    Shanghai 1796236,
    China

    Active - Recruiting

  • Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    Shanghai 1796236, 200092
    China

    Active - Recruiting

  • Shenyang Fourth People's Hospital

    Shenyang, 110031
    China

    Site Not Available

  • Shenyang Fourth People's Hospital

    Shenyang 2034937, 110031
    China

    Site Not Available

  • Shenzhen Eye Hospital

    Shenzhen, 518040
    China

    Site Not Available

  • Shenzhen Eye Hospital

    Shenzhen 1795565, 518040
    China

    Site Not Available

  • Hebei People's Hospital

    Shijiazhuang, 050071
    China

    Site Not Available

  • Hebei People's Hospital

    Shijiazhuang 1795270, 050071
    China

    Site Not Available

  • Shanxi Bethune Hospital

    Taiyuan, 030032
    China

    Site Not Available

  • Shanxi Bethune Hospital

    Taiyuan 1793511, 030032
    China

    Site Not Available

  • Tianjin Eye Hospital

    Tianjin, 300050
    China

    Site Not Available

  • Tianjin Eye Hospital

    Tianjin 1792947, 300050
    China

    Site Not Available

  • Eye Hospital, Wenzhou Medical University

    Wenzhou, 325027
    China

    Site Not Available

  • Eye Hospital, Wenzhou Medical University

    Wenzhou 1791388, 325027
    China

    Site Not Available

  • Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, 430030
    China

    Site Not Available

  • Xiehe Hospital, Tongji Medical College Huazhong University of Science & Technology

    Wuhan, 430022
    China

    Site Not Available

  • Xiehe Hospital, Tongji Medical College Huazhong University of Science & Technology; Opthamology

    Wuhan, 430022
    China

    Active - Recruiting

  • Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan 1791247, 430030
    China

    Active - Recruiting

  • Xiehe Hospital, Tongji Medical College Huazhong University of Science & Technology

    Wuhan 1791247, 430022
    China

    Site Not Available

  • Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan City, 430030
    China

    Site Not Available

  • Xiamen Eye Center Of Xiamen University

    Xiamen, 361000
    China

    Site Not Available

  • Xiamen Eye Center Of Xiamen University

    Xiamen 1790645, 361000
    China

    Site Not Available

  • Hebei Eye Hospital

    Xingtai,
    China

    Site Not Available

  • Hebei Eye Hospital

    Xingtai 1788927,
    China

    Site Not Available

  • Henan Provincial Eye Hosptial

    Zhengzhou, 450003
    China

    Site Not Available

  • Henan Provincial Eye Hosptial

    Zhengzhou 1784658, 450003
    China

    Site Not Available

  • Affiliated Hospital of Zunyi Medical University

    Zunyi, 563000
    China

    Site Not Available

  • Affiliated Hospital of Zunyi Medical University

    Zunyi 1783621, 563000
    China

    Site Not Available

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