StereoEEG Motor Neuronal Potentials Decoding

Last updated: July 21, 2025
Sponsor: Research Center of Neurology, Russia
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

motor tasks

Clinical Study ID

NCT06432907
Stereo-iBCI
  • Ages 18-70
  • All Genders

Study Summary

The goals of this study are (1) to evaluate the rate of stereoEEG brain-computer interface (BCI) classification accuracy and (2) to collect the dataset of neuronal signals recorded from stereoEEG electrodes during motor performance, motor imagery or brain-computer interface control. The study enrolls hospitalised patients suffering from resistant epilepsy with already implanted intracranial stereoEEG electrodes for medical reasons (i.e. for preoperative localization of the epileptogenic foci). The number and location of electrodes are determined solely for the clinical purposes of stereoEEG monitoring and are not related to the protocol of the current study.

After obtaining informed consent to participate in the study, each patient will participate in one experimental session lasting no more than 60 minutes, recording brain signals associated with hand movement, motor imagery, and BCI control. All tasks and instructions presented during the study session are not pro-epileptogenic and cannot provoke an epileptic attack. The experiments will take place in the patient's room, without interruption of observation by the department's medical staff.

The data recorded in this study will be used to improve or develop new algorithms for decoding motor signals from deep brain structures for their potential use in invasive BCIs.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • male and female patients who have had stereoEEG electrodes implanted for medicalreasons;

  • voluntary informed consent to participate in the study;

  • age from 18 to 70 years.

Exclusion

Exclusion Criteria:

  • patient refusal to participate in the study;

  • cognitive impairment that prevents following the study instructions;

  • severe visual impairment that does not allow viewing visual instructions on acomputer screen;

  • upper limb paresis or other motor disorders;

  • pain in the hand of any etiology;

  • any acute diseases, exacerbation of chronic diseases, acute life-threateningconditions;

  • occurrence of an epileptic attack during the experiment.

Study Design

Total Participants: 30
Treatment Group(s): 1
Primary Treatment: motor tasks
Phase:
Study Start date:
June 06, 2024
Estimated Completion Date:
December 25, 2026

Connect with a study center

  • Research center of neurology, Department of neurorehabilitation and physiotherapy

    Moscow, 125367
    Russian Federation

    Active - Recruiting

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