Resilient Together for Dementia

Last updated: March 25, 2025
Sponsor: Icahn School of Medicine at Mount Sinai
Overall Status: Completed

Phase

N/A

Condition

Dementia

Treatment

Resilient Together for Dementia

Clinical Study ID

NCT06421545
GCO 23-0519
1K23AG075188-01A1
  • Ages > 65
  • All Genders

Study Summary

The proposed study will establish the feasibility, acceptability and credibility of a novel live video dyadic resiliency intervention, Resilient Together for Dementia (RT-D), aimed at preventing chronic emotional distress and preserving quality of life among dyads at risk for chronic emotional distress early after a diagnosis of Alzheimer's disease or a related dementia (ADRD).

Eligibility Criteria

Inclusion

PWD inclusion criteria are:

  • Recent (~1 month) chart documented ADRD diagnosis,

  • ADRD symptom onset after age 65 ,

  • cognitive assessment scores and symptoms consistent with early stage dementia, asdetermined by the Clinical Dementia Rating Scale scores of .5 or 1.0

  • cognitive awareness of his/her problems (as determined by the treating neurologist),and

  • ability to understand study and research protocol, as determined by a standardizedteach-back method assessment84.

Additional inclusion criteria for dyads are:

  • English speaking adults (18 years or older),

  • dyad lives together,

  • at least one partner endorses clinically significant emotional distress duringscreening (>7 on Hospital Anxiety and Depression scale subscales)

Exclusion

Exclusion Criteria:

  • patient is deemed inappropriate by the neurology team,

  • either partner has a co-occurring terminal illness,

  • patient was diagnosed with forms of dementia with clinical profiles that wouldpreclude participation (e.g., Frontotemporal Dementia- behavioral variant), asdetermined by treatment team.

Study Design

Total Participants: 12
Treatment Group(s): 1
Primary Treatment: Resilient Together for Dementia
Phase:
Study Start date:
April 19, 2024
Estimated Completion Date:
March 06, 2025

Study Description

Both persons living with dementia (PWDs) and their spousal care-partners experience high levels of clinically elevated emotional distress, which can become chronic without treatment and negatively impact the health, quality of life, communication, and care-planning of both partners. A tailored dyadic intervention, such as the proposed Resilient Together for Dementia, delivered over live video to this at risk population during the window of opportunity when PWDs can participate has the potential to prevent chronic emotional distress and preserve quality of life for PWDs and their loved ones.

Connect with a study center

  • Brain Injury Research Center at Mount Sinai

    New York, New York 10029
    United States

    Site Not Available

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